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- W3027407614 abstract "An unprecedented domino protocol for the novel synthesis of highly diverse and functionalized tetrahydro pyranopyrazole scaffolds using chalcone epoxide has been reported for the first time. This synthetic protocol generates three consecutive stereogenic centres in a highly diastereoselective manner with the formation of vicinal diol and a quaternary carbon centre. A wide range of substrates were utilized for the scope of this methodology and provided very good yields of pyranopyrazoles. The pyranopyrazoles were also transformed into densely functionalized tetrasubstituted olefins." @default.
- W3027407614 created "2020-05-29" @default.
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- W3027407614 date "2020-01-01" @default.
- W3027407614 modified "2023-10-17" @default.
- W3027407614 title "Cascade annulation reaction (CAR): highly diastereoselective synthesis of pyranopyrazole scaffolds" @default.
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- W3027407614 doi "https://doi.org/10.1039/d0ra03400b" @default.
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