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- W302774911 abstract "Hitherto, formation of new blood vessels was usually classified into two well-known embryological phenomenons: vasculogenesis and angiogenesis. Vasculogenesis is described as a primary in situ differentiation of endothelial cells from mesodermal precursors, leading to the formation of primary capillary poleaxe. Angiogenesis was thought to be exclusively the result of vessels’ sprouting from pre-existing vessels. But recently, Asahara et al. have showed that circulating endothelial cell progenitors are also involved in the angiogenic process [1]. Concerning collateral vessel formation, a third concept, called “arteriogenesis” has been introduced by Schapper [2]. It consists of the remodeling of small capillaries into larger arterioles, with a muscular layer. Nevertheless, those three entities require: proliferation and migration with a spatial organisation of endothelial cellsdissolution and regeneration of the vascular extracellular matrix, considered as vascular stakeparticipation of mesenchymal perivascular cells (smooth muscle cells and pericytes)." @default.
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- W302774911 date "1999-01-01" @default.
- W302774911 modified "2023-10-18" @default.
- W302774911 title "Angiogenic Growth Factors" @default.
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- W302774911 doi "https://doi.org/10.1007/978-0-585-38146-6_6" @default.
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