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• W3027780319 endingPage "101574" @default.
• W3027780319 startingPage "101574" @default.
• W3027780319 abstract "Psychiatric disorders and childhood trauma are highly prevalent in female inmates. Brain-derived neurotrophic factor (BDNF) plays a number of roles in neuronal survival, structure, and function. Data in the literature suggest that it is a neurobiological substrate that moderates the impact of childhood adversities on the late expression of psychiatric disorders. The aim of this study was to determine whether five childhood trauma subtypes—physical abuse, sexual abuse, emotional abuse, physical neglect, and emotional neglect—are associated with adult psychiatric disorders, BDNF levels, and criminality among incarcerated women. This was a cross-sectional study involving a consecutive sample of 110 women, divided into three groups of women (forensic - mentally ill who committed crimes, clinical psychiatric inpatients and healthy controls). The Childhood Trauma Questionnaire and the Mini-International Neuropsychiatric Interview-Plus were applied in the whole sample, and BDNF levels were measured in a sub-sample of 54 women. The rates of mental illness and childhood trauma were high in the forensic group. Emotional abuse was higher in the clinical and forensic groups than in the healthy control group. Lower BDNF levels were associated with emotional abuse in the forensic group as well as with sexual abuse in the healthy control group. After multinomial logistic regression, lower levels of BDNF, higher levels of emotional abuse and the presence of familial offense were considered factors related to clinical psychiatric group. The results of this study underscore the idea that BDNF may be an important factor related to the development of diseases and criminality in women who are victims of childhood trauma, becoming a possible biological marker." @default.
• W3027780319 created "2020-05-29" @default.
• W3027780319 creator A5025897822 @default.
• W3027780319 creator A5046951714 @default.
• W3027780319 creator A5066970174 @default.
• W3027780319 creator A5076806284 @default.
• W3027780319 date "2020-07-01" @default.
• W3027780319 modified "2023-10-03" @default.
• W3027780319 title "Childhood trauma, psychiatric disorders, and criminality in women: Associations with serum levels of brain-derived neurotrophic factor" @default.
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• W3027780319 doi "https://doi.org/10.1016/j.ijlp.2020.101574" @default.
• W3027780319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32768114" @default.
• W3027780319 hasPublicationYear "2020" @default.
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