Matches in SemOpenAlex for { <https://semopenalex.org/work/W3027831610> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W3027831610 endingPage "1105" @default.
- W3027831610 startingPage "1099" @default.
- W3027831610 abstract "Monitoring uterine cyclic GMP levels in the rat revealed that there was a statistically significant rise at proestrus from the values that are found at other stages of the cycle (estrus, metestrus, diestrus). Concurrent with the increase in cyclic GMP at proestrus was a decrease in cyclic AMP levels. Treatment of ovariectomized rats with estradiol benzoate (1 μg daily for 4 days) caused an increase in uterine cycle GMP levels from 0·04 to 0·10 pmol/mg tissue. Co-administration of progesterone (4 mg/day for 4 days) blocked this estrogen response. Studies of prostaglandin levels in the cycling rat revealed a rise in PGF occurred at proestrus. That the alteration in PGF levels is estrogen related was evident by the fact that treatment of ovariectomized rats with estradiol benzoate (1 ·μg daily for 4 days) caused a large increase in PGF levels. This action of estrogen upon prostaglandin levels was blocked by co-administration of progesterone (4 mg/day for 4 days). There is clearly a temporal interrelationship between the action of estrogen to increase cyclic GMP and PGF levels. The ability of the prostaglandin synthetase inhibitor, indomethacin, to block the estrogen-induced increase in PGF, with no inhibitory action upon cyclic GMP formation, requires the formation of these two substances to be independent of each other, or the increment in PGF to follow that of cyclic GMP." @default.
- W3027831610 created "2020-05-29" @default.
- W3027831610 creator A5000709346 @default.
- W3027831610 creator A5007195014 @default.
- W3027831610 creator A5051237655 @default.
- W3027831610 creator A5059479321 @default.
- W3027831610 date "1976-01-01" @default.
- W3027831610 modified "2023-09-27" @default.
- W3027831610 title "ESTROGEN-INDUCED ALTERATIONS IN CYCLIC NUCLEOTIDE AND PROSTAGLANDIN LEVELS IN TARGET TISSUE" @default.
- W3027831610 cites W1963644679 @default.
- W3027831610 cites W1976275849 @default.
- W3027831610 cites W1980431793 @default.
- W3027831610 cites W1993921683 @default.
- W3027831610 cites W1996466550 @default.
- W3027831610 cites W1996732665 @default.
- W3027831610 cites W2002497773 @default.
- W3027831610 cites W2006936285 @default.
- W3027831610 cites W2038929693 @default.
- W3027831610 cites W2044866113 @default.
- W3027831610 cites W2052240378 @default.
- W3027831610 cites W2065809908 @default.
- W3027831610 cites W2069161066 @default.
- W3027831610 cites W2076147535 @default.
- W3027831610 cites W2088566793 @default.
- W3027831610 cites W2111648388 @default.
- W3027831610 cites W2165848911 @default.
- W3027831610 doi "https://doi.org/10.1016/b978-0-08-019682-4.50153-0" @default.
- W3027831610 hasPublicationYear "1976" @default.
- W3027831610 type Work @default.
- W3027831610 sameAs 3027831610 @default.
- W3027831610 citedByCount "0" @default.
- W3027831610 crossrefType "book-chapter" @default.
- W3027831610 hasAuthorship W3027831610A5000709346 @default.
- W3027831610 hasAuthorship W3027831610A5007195014 @default.
- W3027831610 hasAuthorship W3027831610A5051237655 @default.
- W3027831610 hasAuthorship W3027831610A5059479321 @default.
- W3027831610 hasConcept C126322002 @default.
- W3027831610 hasConcept C134018914 @default.
- W3027831610 hasConcept C185592680 @default.
- W3027831610 hasConcept C1998276 @default.
- W3027831610 hasConcept C2777164284 @default.
- W3027831610 hasConcept C2777198256 @default.
- W3027831610 hasConcept C2778506572 @default.
- W3027831610 hasConcept C2780664492 @default.
- W3027831610 hasConcept C71924100 @default.
- W3027831610 hasConcept C8264082 @default.
- W3027831610 hasConcept C86803240 @default.
- W3027831610 hasConceptScore W3027831610C126322002 @default.
- W3027831610 hasConceptScore W3027831610C134018914 @default.
- W3027831610 hasConceptScore W3027831610C185592680 @default.
- W3027831610 hasConceptScore W3027831610C1998276 @default.
- W3027831610 hasConceptScore W3027831610C2777164284 @default.
- W3027831610 hasConceptScore W3027831610C2777198256 @default.
- W3027831610 hasConceptScore W3027831610C2778506572 @default.
- W3027831610 hasConceptScore W3027831610C2780664492 @default.
- W3027831610 hasConceptScore W3027831610C71924100 @default.
- W3027831610 hasConceptScore W3027831610C8264082 @default.
- W3027831610 hasConceptScore W3027831610C86803240 @default.
- W3027831610 hasLocation W30278316101 @default.
- W3027831610 hasOpenAccess W3027831610 @default.
- W3027831610 hasPrimaryLocation W30278316101 @default.
- W3027831610 hasRelatedWork W1985546601 @default.
- W3027831610 hasRelatedWork W2034402330 @default.
- W3027831610 hasRelatedWork W2060297995 @default.
- W3027831610 hasRelatedWork W2071688816 @default.
- W3027831610 hasRelatedWork W2092722075 @default.
- W3027831610 hasRelatedWork W2156499301 @default.
- W3027831610 hasRelatedWork W2167902350 @default.
- W3027831610 hasRelatedWork W2169978493 @default.
- W3027831610 hasRelatedWork W3027831610 @default.
- W3027831610 hasRelatedWork W2067979510 @default.
- W3027831610 isParatext "false" @default.
- W3027831610 isRetracted "false" @default.
- W3027831610 magId "3027831610" @default.
- W3027831610 workType "book-chapter" @default.