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- W3027842783 abstract "Among the metabolites of fluocortolone (IV), isolated from human urine, there was found fluocortolone-21-acid (XI). This metabolite and several ester derivatives were synthesized by different routes starting from fluocortolone. The synthetic methods used to prepare the fluocortolone acid esters were extended to other corticoid derivatives. Several pregnan-21-oic acid esters possess the unique activity that they are topical anti-inflammatory agents with no side effects. Even when administered at high dosages, the usual systemic activity associated with corticosteroid treatment could not be observed." @default.
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- W3027842783 date "1976-01-01" @default.
- W3027842783 modified "2023-09-28" @default.
- W3027842783 title "NEW BIOLOGICALLY ACTIVE PREGNAN-21-OIC ACID ESTERS" @default.
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- W3027842783 doi "https://doi.org/10.1016/b978-0-08-019682-4.50011-1" @default.
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