Matches in SemOpenAlex for { <https://semopenalex.org/work/W3028016679> ?p ?o ?g. }
- W3028016679 endingPage "122817" @default.
- W3028016679 startingPage "122817" @default.
- W3028016679 abstract "Benefits of indoor air filtration in heavily polluted areas are not fully understood. This study aims to examine whether short-term air filtration intervention could attenuate the hazards from acute exposure to fine particulate matter (PM2.5), and investigate the potential impact on inflammatory cytokines and DNA methylation. A randomized, double-blind crossover trial of true or sham indoor air filtration was conducted among 29 healthy young adults in Beijing, China. Each episode covered a typical air pollution wave, and 38 cytokines and DNAm of 20 genes were measured at 3 time points: pre-smog, during smog, and post-smog. Linear mixed-effect models were used to evaluate the associations. The indoor PM2.5 concentration with true filtration was 67.8 % lower than sham filtration (13.8 μg/m3 vs. 42.8 μg/m3). Air filtration was significantly associated with the decreases in 9 cytokines, from 6.61 % to 21.24 %. PM2.5 exposure was significantly associated with elevated levels of 9 cytokines and changed methylation at 7 CpG sites. Notably, PM2.5 was significantly associated with GM-CSF, sCD40L, MCP-1, and FGF-2, as well as methylation in corresponding genes, but no mediation effect was observed. This trial suggested that indoor air filtration might attenuate the adverse effects of PM2.5 exposure through changing cytokines and DNAm." @default.
- W3028016679 created "2020-05-29" @default.
- W3028016679 creator A5000465383 @default.
- W3028016679 creator A5019243855 @default.
- W3028016679 creator A5023065753 @default.
- W3028016679 creator A5035358476 @default.
- W3028016679 creator A5040704785 @default.
- W3028016679 creator A5044639574 @default.
- W3028016679 creator A5049813480 @default.
- W3028016679 creator A5050151730 @default.
- W3028016679 creator A5052813770 @default.
- W3028016679 creator A5059241196 @default.
- W3028016679 creator A5071427974 @default.
- W3028016679 creator A5076717825 @default.
- W3028016679 creator A5081487015 @default.
- W3028016679 creator A5083692529 @default.
- W3028016679 creator A5086124785 @default.
- W3028016679 date "2020-11-01" @default.
- W3028016679 modified "2023-10-12" @default.
- W3028016679 title "Inflammatory cytokines and DNA methylation in healthy young adults exposure to fine particulate matter: A randomized, double-blind crossover trial of air filtration" @default.
- W3028016679 cites W180853016 @default.
- W3028016679 cites W1982498199 @default.
- W3028016679 cites W2001494483 @default.
- W3028016679 cites W2010264557 @default.
- W3028016679 cites W2026149693 @default.
- W3028016679 cites W2029247904 @default.
- W3028016679 cites W2043677945 @default.
- W3028016679 cites W2050112556 @default.
- W3028016679 cites W2051962533 @default.
- W3028016679 cites W2055986128 @default.
- W3028016679 cites W2063407989 @default.
- W3028016679 cites W2063932784 @default.
- W3028016679 cites W2066935845 @default.
- W3028016679 cites W2087403652 @default.
- W3028016679 cites W2093656216 @default.
- W3028016679 cites W2096001387 @default.
- W3028016679 cites W2099777739 @default.
- W3028016679 cites W2117155159 @default.
- W3028016679 cites W2140282454 @default.
- W3028016679 cites W2141530703 @default.
- W3028016679 cites W2144428405 @default.
- W3028016679 cites W2146532249 @default.
- W3028016679 cites W2148894953 @default.
- W3028016679 cites W2150751323 @default.
- W3028016679 cites W2158480275 @default.
- W3028016679 cites W2184655932 @default.
- W3028016679 cites W2261930191 @default.
- W3028016679 cites W2395847301 @default.
- W3028016679 cites W2408433496 @default.
- W3028016679 cites W2463323383 @default.
- W3028016679 cites W2497879403 @default.
- W3028016679 cites W2529024004 @default.
- W3028016679 cites W2534879302 @default.
- W3028016679 cites W2557512835 @default.
- W3028016679 cites W2596362505 @default.
- W3028016679 cites W2747001950 @default.
- W3028016679 cites W2750633386 @default.
- W3028016679 cites W2762582402 @default.
- W3028016679 cites W2789459927 @default.
- W3028016679 cites W2791740451 @default.
- W3028016679 cites W2886559274 @default.
- W3028016679 cites W2911074926 @default.
- W3028016679 cites W2911727943 @default.
- W3028016679 cites W2921788575 @default.
- W3028016679 cites W2935975501 @default.
- W3028016679 cites W2940004630 @default.
- W3028016679 cites W2962764361 @default.
- W3028016679 cites W2963509131 @default.
- W3028016679 cites W2967067904 @default.
- W3028016679 cites W2969621686 @default.
- W3028016679 cites W3007984821 @default.
- W3028016679 cites W409124881 @default.
- W3028016679 doi "https://doi.org/10.1016/j.jhazmat.2020.122817" @default.
- W3028016679 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32516725" @default.
- W3028016679 hasPublicationYear "2020" @default.
- W3028016679 type Work @default.
- W3028016679 sameAs 3028016679 @default.
- W3028016679 citedByCount "19" @default.
- W3028016679 countsByYear W30280166792021 @default.
- W3028016679 countsByYear W30280166792022 @default.
- W3028016679 countsByYear W30280166792023 @default.
- W3028016679 crossrefType "journal-article" @default.
- W3028016679 hasAuthorship W3028016679A5000465383 @default.
- W3028016679 hasAuthorship W3028016679A5019243855 @default.
- W3028016679 hasAuthorship W3028016679A5023065753 @default.
- W3028016679 hasAuthorship W3028016679A5035358476 @default.
- W3028016679 hasAuthorship W3028016679A5040704785 @default.
- W3028016679 hasAuthorship W3028016679A5044639574 @default.
- W3028016679 hasAuthorship W3028016679A5049813480 @default.
- W3028016679 hasAuthorship W3028016679A5050151730 @default.
- W3028016679 hasAuthorship W3028016679A5052813770 @default.
- W3028016679 hasAuthorship W3028016679A5059241196 @default.
- W3028016679 hasAuthorship W3028016679A5071427974 @default.
- W3028016679 hasAuthorship W3028016679A5076717825 @default.
- W3028016679 hasAuthorship W3028016679A5081487015 @default.
- W3028016679 hasAuthorship W3028016679A5083692529 @default.
- W3028016679 hasAuthorship W3028016679A5086124785 @default.
- W3028016679 hasConcept C104317684 @default.