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- W3028102836 abstract "Co-stimulatory T-cell inhibitors are used in the treatment of rheumatoid arthritis and to prevent rejection of renal transplants. Inhibitors of the intereukin (IL-17) cytokine are indicated for psoriasis, psoriatic arthritis and ankylosing spondylitis and anti- IL-23 drugs for psoriasis. Serious infections occur in 4.2% to 25.0% of co-stimulatory inhibitors and 1.0% to 2.0% with IL-17 or IL-23 inhibitors. Underlying disease, steroid dose greater than 7.5 to 10.0 mg, and comorbidities influence risk in individual patients. Opportunistic infections or reactivation of tuberculosis are rare." @default.
- W3028102836 created "2020-05-29" @default.
- W3028102836 creator A5064324051 @default.
- W3028102836 date "2020-06-01" @default.
- W3028102836 modified "2023-10-18" @default.
- W3028102836 title "Risk of Serious Infection Associated with Agents that Target T-Cell Activation and Interleukin-17 and Interleukin-23 Cytokines" @default.
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- W3028102836 doi "https://doi.org/10.1016/j.idc.2020.02.001" @default.
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