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• W3028159371 endingPage "4089" @default.
• W3028159371 startingPage "4078" @default.
• W3028159371 abstract "Neurotransmitter switching is a form of brain plasticity in which an environmental stimulus causes neurons to replace one neurotransmitter with another, often resulting in changes in behavior. This raises the possibility of applying a specific environmental stimulus to induce a switch that can enhance a desirable behavior or ameliorate symptoms of a specific pathology. For example, a stimulus inducing an increase in the number of neurons expressing dopamine could treat Parkinson's disease, or one affecting the number expressing serotonin could alleviate depression. This may already be producing successful treatment outcomes without our knowing that transmitter switching is involved, with improvement of motor function through physical activity and cure of seasonal depression with phototherapy. This review presents prospects for future investigation of neurotransmitter switching, considering opportunities and challenges for future research and describing how the investigation of transmitter switching is likely to evolve with new tools, thus reshaping our understanding of both normal brain function and mental illness." @default.
• W3028159371 created "2020-05-29" @default.
• W3028159371 creator A5051858605 @default.
• W3028159371 creator A5054098339 @default.
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• W3028159371 creator A5070671062 @default.
• W3028159371 creator A5073849037 @default.
• W3028159371 date "2020-05-20" @default.
• W3028159371 modified "2023-10-17" @default.
• W3028159371 title "Decoding Neurotransmitter Switching: The Road Forward" @default.
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