FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3028543662> ?p ?o ?g. }

• W3028543662 endingPage "1693" @default.
• W3028543662 startingPage "1684" @default.
• W3028543662 abstract "Epithelial ovarian cancer (EOC) is the most common cause of death among gynecological cancers. FOXP3 gene is the most dependable marker for regulatory T cells (Treg) which play a major role in immune tolerance. The aim of this study was to explore whether the FOXP3 gene polymorphisms (rs3761548 A/C and rs5902434del/ATT) were associated susceptibility and prognosis for EOC.A total of 455 ovarian cancer patients and 337 healthy female controls were enrolled. Genotyping of FOXP3 polymorphisms rs3761548 A/C was determined by polymerase chain reaction-restrictive fragment length polymorphism (PCR-RFLP), while rs5902434 del/ATT was directly visualized in a 6% polyacrylamide gel electrophoresis stained after PCR. Kaplan-Meier method and Cox regression analysis were used to find an association between the FOXP3 gene and survival of EOC patients.Data showed that AC genotype of FOXP3 rs3761548 was associated with the high susceptibility of EOC (overdominant model: OR=1.42, 95% CI=1.07-1.89, P=0.015), while AA genotype showed lower risk for ovarian cancer compared with CC/AC genotypes (OR=0.45, 95% CI=0.23-0.90, P=0.022). In contrast, there were no significant differences for rs5902434 polymorphism of FOXP3 in ovarian cancer patients and controls. However, del/ATT genotype might be an independent risk factor for EOC prognosis in the dominant (HR=2.60, 95% CI=1.26-5.38, P=0.010) and overdominant (HR=2.46, 95% CI=1.31-4.61, P=0.005) models.Our findings suggest that rs3761548 could contribute to EOC risk in a Chinese Han population. Rs5902434 polymorphisms might be a marker to identify high risk patients." @default.
• W3028543662 created "2020-05-29" @default.
• W3028543662 creator A5004886413 @default.
• W3028543662 creator A5007320512 @default.
• W3028543662 creator A5011157307 @default.
• W3028543662 creator A5013083142 @default.
• W3028543662 creator A5029300197 @default.
• W3028543662 creator A5034172662 @default.
• W3028543662 creator A5046597133 @default.
• W3028543662 creator A5050616688 @default.
• W3028543662 creator A5059860825 @default.
• W3028543662 creator A5062751124 @default.
• W3028543662 creator A5073494318 @default.
• W3028543662 creator A5076623908 @default.
• W3028543662 creator A5086664284 @default.
• W3028543662 creator A5091350871 @default.
• W3028543662 date "2018-01-01" @default.
• W3028543662 modified "2023-09-28" @default.
• W3028543662 title "Transcription factor FOXP3 gene variants affect epithelial ovarian carcinoma in the Han Chinese population." @default.
• W3028543662 cites W1176076248 @default.
• W3028543662 cites W1969288772 @default.
• W3028543662 cites W1971546950 @default.
• W3028543662 cites W1974740739 @default.
• W3028543662 cites W1987924345 @default.
• W3028543662 cites W1991746131 @default.
• W3028543662 cites W2000471395 @default.
• W3028543662 cites W2005451808 @default.
• W3028543662 cites W2009900335 @default.
• W3028543662 cites W2021112078 @default.
• W3028543662 cites W2043310037 @default.
• W3028543662 cites W2057281059 @default.
• W3028543662 cites W2065486667 @default.
• W3028543662 cites W2070369494 @default.
• W3028543662 cites W2074171712 @default.
• W3028543662 cites W2075131034 @default.
• W3028543662 cites W2109351460 @default.
• W3028543662 cites W2116815997 @default.
• W3028543662 cites W2137074525 @default.
• W3028543662 cites W2141983743 @default.
• W3028543662 cites W2146689565 @default.
• W3028543662 cites W2147475006 @default.
• W3028543662 cites W2152930579 @default.
• W3028543662 cites W2160047041 @default.
• W3028543662 cites W2160458616 @default.
• W3028543662 cites W2187109277 @default.
• W3028543662 cites W2320569320 @default.
• W3028543662 cites W2558317907 @default.
• W3028543662 cites W2584617802 @default.
• W3028543662 cites W2737785069 @default.
• W3028543662 cites W3013868404 @default.
• W3028543662 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6958113" @default.
• W3028543662 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31938270" @default.
• W3028543662 hasPublicationYear "2018" @default.
• W3028543662 type Work @default.
• W3028543662 sameAs 3028543662 @default.
• W3028543662 citedByCount "1" @default.
• W3028543662 countsByYear W30285436622021 @default.
• W3028543662 crossrefType "journal-article" @default.
• W3028543662 hasAuthorship W3028543662A5004886413 @default.
• W3028543662 hasAuthorship W3028543662A5007320512 @default.
• W3028543662 hasAuthorship W3028543662A5011157307 @default.
• W3028543662 hasAuthorship W3028543662A5013083142 @default.
• W3028543662 hasAuthorship W3028543662A5029300197 @default.
• W3028543662 hasAuthorship W3028543662A5034172662 @default.
• W3028543662 hasAuthorship W3028543662A5046597133 @default.
• W3028543662 hasAuthorship W3028543662A5050616688 @default.
• W3028543662 hasAuthorship W3028543662A5059860825 @default.
• W3028543662 hasAuthorship W3028543662A5062751124 @default.
• W3028543662 hasAuthorship W3028543662A5073494318 @default.
• W3028543662 hasAuthorship W3028543662A5076623908 @default.
• W3028543662 hasAuthorship W3028543662A5086664284 @default.
• W3028543662 hasAuthorship W3028543662A5091350871 @default.
• W3028543662 hasConcept C104317684 @default.
• W3028543662 hasConcept C121608353 @default.
• W3028543662 hasConcept C126322002 @default.
• W3028543662 hasConcept C135763542 @default.
• W3028543662 hasConcept C143998085 @default.
• W3028543662 hasConcept C203014093 @default.
• W3028543662 hasConcept C2779727006 @default.
• W3028543662 hasConcept C2780427987 @default.
• W3028543662 hasConcept C31467283 @default.
• W3028543662 hasConcept C54355233 @default.
• W3028543662 hasConcept C71924100 @default.
• W3028543662 hasConcept C86803240 @default.
• W3028543662 hasConcept C8891405 @default.
• W3028543662 hasConcept C90924648 @default.
• W3028543662 hasConceptScore W3028543662C104317684 @default.
• W3028543662 hasConceptScore W3028543662C121608353 @default.
• W3028543662 hasConceptScore W3028543662C126322002 @default.
• W3028543662 hasConceptScore W3028543662C135763542 @default.
• W3028543662 hasConceptScore W3028543662C143998085 @default.
• W3028543662 hasConceptScore W3028543662C203014093 @default.
• W3028543662 hasConceptScore W3028543662C2779727006 @default.
• W3028543662 hasConceptScore W3028543662C2780427987 @default.
• W3028543662 hasConceptScore W3028543662C31467283 @default.
• W3028543662 hasConceptScore W3028543662C54355233 @default.
• W3028543662 hasConceptScore W3028543662C71924100 @default.
• W3028543662 hasConceptScore W3028543662C86803240 @default.

• next