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- W3028634710 abstract "目的 评价半导体倍频激光诱导棕色挪威(BN)大鼠脉络膜新生血管(CNV)模型的可行性.方法 32只BN大鼠行半导体倍频激光(波长532 nm)眼底光凝,6只作为正常对照.激光功率、光凝斑直径和曝光时间分别为525 mW、50 μm及0.05 s.分别在光凝后7、21、35、63 d随机各选取8只大鼠行眼底照像、荧光素眼底血管造影(FFA)和吲哚青绿眼底血管造影(ICGA)检查.眼球标本行脉络膜巩膜铺片新生血管定量分析和组织病理切片光镜、免疫组织化学染色观察.结果 FFA和ICGA检查发现光凝后7 d CNV形成,21～35 d形成高峰期,63 d后生成减少.脉络膜巩膜铺片新生血管定量分析和组织病理学检查,均见光凝后21、35 d CNV的形成与7、63 d比较差异有显著统计学意义(P＜0.01).结论 脉络膜巩膜铺片新生血管分析及免疫组织化学染色是实验性CNV定量研究的有效手段。" @default.
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- W3028634710 date "2007-01-15" @default.
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- W3028634710 title "Quantitative image analysis of laser-induced choroidal neovascularization in rat" @default.
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