Matches in SemOpenAlex for { <https://semopenalex.org/work/W3028653669> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3028653669 endingPage "141" @default.
- W3028653669 startingPage "138" @default.
- W3028653669 abstract "Objective To investigate the changes of cytokines in rats with Clonorchiasis and the protective effects of Milkvetch Root on liver tissue.Methods Adult 32 male rats were randomly divided into four groups:control group,model group,Albendazole (ALB) group and Albendazole combined with Milkvetch Root (ALB + MR) group (8 rats / group).The experimental rats were infected with 50 metacercariae of C.sinensis or equal physiological saline through a gavage needle.The ALB group and ALB + MR group received ALB (50mg/kg/d) orally for 5days,or with MR intraperitoneally (800 mg/kg/d) for 30 days.All rats were sacrificed after 14 weeks of infection.Histopathological examination of rats' livers was performed.The levels of IL-2 and IL-4 in the serum of the rats were detected by ELISA assays.Results The vacuolization of hepatocytes and infiltration of white cells were observed in the model group,but did not observed in control group under light microscope.The injury of liver tissue of rats in ALB + MR group was milder than ALB group.The level of IL-4 in serum of rats in model group increased significantly(F =10.44,P =0.003 4),but the level of IL-2 decreased significantly compared with control group (F =18.3,P =0.000 2).The level of IL-4 in serum of rats in ALB group and in A LB + MR group decreased significantly (F =9.69,P =0.0046 ; F =7.61,P =0.010 7),while the level of IL-2 of rats in ALB group and in ALB + MR group increased significantly (F =8.69,P =0.006 8 ; F =5.5,P =0.027 3).Conclusion Our results suggested that IL-2 and IL-4 were involved in the pathogenesis of clonorchis sinensis.Milkvetch Root could provide protection to the liver tissue against Clonorchis sinensis,which might associate with the regulation of disturbed cytokines.Key words: Clonorchis sinensis ; Cytokine ; Milkvetch Root; Albendazole" @default.
- W3028653669 created "2020-06-05" @default.
- W3028653669 creator A5000380981 @default.
- W3028653669 creator A5028983129 @default.
- W3028653669 creator A5077153113 @default.
- W3028653669 date "2013-03-05" @default.
- W3028653669 modified "2023-09-28" @default.
- W3028653669 title "The effect of Albendazole combined with Milkvetch Root on hepatic injury in rats with clonorchiasis" @default.
- W3028653669 doi "https://doi.org/10.3760/cma.j.issn.1673-4394.2013.02.012" @default.
- W3028653669 hasPublicationYear "2013" @default.
- W3028653669 type Work @default.
- W3028653669 sameAs 3028653669 @default.
- W3028653669 citedByCount "0" @default.
- W3028653669 crossrefType "journal-article" @default.
- W3028653669 hasAuthorship W3028653669A5000380981 @default.
- W3028653669 hasAuthorship W3028653669A5028983129 @default.
- W3028653669 hasAuthorship W3028653669A5077153113 @default.
- W3028653669 hasConcept C126322002 @default.
- W3028653669 hasConcept C134018914 @default.
- W3028653669 hasConcept C141071460 @default.
- W3028653669 hasConcept C142724271 @default.
- W3028653669 hasConcept C165901193 @default.
- W3028653669 hasConcept C203014093 @default.
- W3028653669 hasConcept C2775879618 @default.
- W3028653669 hasConcept C2777065887 @default.
- W3028653669 hasConcept C2777397205 @default.
- W3028653669 hasConcept C2778614373 @default.
- W3028653669 hasConcept C71924100 @default.
- W3028653669 hasConcept C86803240 @default.
- W3028653669 hasConceptScore W3028653669C126322002 @default.
- W3028653669 hasConceptScore W3028653669C134018914 @default.
- W3028653669 hasConceptScore W3028653669C141071460 @default.
- W3028653669 hasConceptScore W3028653669C142724271 @default.
- W3028653669 hasConceptScore W3028653669C165901193 @default.
- W3028653669 hasConceptScore W3028653669C203014093 @default.
- W3028653669 hasConceptScore W3028653669C2775879618 @default.
- W3028653669 hasConceptScore W3028653669C2777065887 @default.
- W3028653669 hasConceptScore W3028653669C2777397205 @default.
- W3028653669 hasConceptScore W3028653669C2778614373 @default.
- W3028653669 hasConceptScore W3028653669C71924100 @default.
- W3028653669 hasConceptScore W3028653669C86803240 @default.
- W3028653669 hasIssue "02" @default.
- W3028653669 hasLocation W30286536691 @default.
- W3028653669 hasOpenAccess W3028653669 @default.
- W3028653669 hasPrimaryLocation W30286536691 @default.
- W3028653669 hasRelatedWork W1444146890 @default.
- W3028653669 hasRelatedWork W2351857290 @default.
- W3028653669 hasRelatedWork W2355247605 @default.
- W3028653669 hasRelatedWork W2356558875 @default.
- W3028653669 hasRelatedWork W2360800932 @default.
- W3028653669 hasRelatedWork W2371130897 @default.
- W3028653669 hasRelatedWork W2374590248 @default.
- W3028653669 hasRelatedWork W2376336064 @default.
- W3028653669 hasRelatedWork W2379913183 @default.
- W3028653669 hasRelatedWork W2384327212 @default.
- W3028653669 hasRelatedWork W2385260502 @default.
- W3028653669 hasRelatedWork W2388847289 @default.
- W3028653669 hasRelatedWork W2392196464 @default.
- W3028653669 hasRelatedWork W2398293668 @default.
- W3028653669 hasRelatedWork W2465343545 @default.
- W3028653669 hasRelatedWork W3020013719 @default.
- W3028653669 hasRelatedWork W3029715514 @default.
- W3028653669 hasRelatedWork W3031624981 @default.
- W3028653669 hasRelatedWork W3145953781 @default.
- W3028653669 hasRelatedWork W2607479078 @default.
- W3028653669 hasVolume "36" @default.
- W3028653669 isParatext "false" @default.
- W3028653669 isRetracted "false" @default.
- W3028653669 magId "3028653669" @default.
- W3028653669 workType "article" @default.