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- W3028680565 abstract "Routinely used automated immunoassays have been found to give unrealiable measurements of thyroid hormones in the presence of either high or low levels of thyroxine-binding globulin. Thyroid hormones are not the only analytes bound to specific binding proteins that are measured by immunoassays. Preliminary data from a series of cases, comparing IA measurements to those obtained by liquid chromatography-tandem mass spectrometry, reveal for the first time that IA measurements report falsely low (by an average of 27%) serum cortisol concentrations. Initial findings suggest that IA measurements of serum cortisol are affected by high concentrations of corticosteroid binding globulin." @default.
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- W3028680565 date "2020-01-01" @default.
- W3028680565 modified "2023-10-12" @default.
- W3028680565 title "Are serum cortisol measurements by immunoassays reliable?" @default.
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- W3028680565 doi "https://doi.org/10.18103/mra.v8i5.2128" @default.
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