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- W3028692357 abstract "The pathogenesis of acne rosacea has not been fully elucidated, and its treatment lacks theoretical basis and specificity. In recent years, studies have found that patients with acne rosacea harbor predisposing genes or mutations in genes related to neuroregulatory and angioregulatory receptors. Under the stimulation with causative factors(such as mites, glucocorticoids, ultraviolet rays, etc), skin-derived antimicrobial peptides are activated abnormally followed by impairment of skin barrier function, and nerves release neuropeptides which directly or indirectly take part in skin immune reaction, affect vasodilatation, and eventually lead to the occurrence of acne rosacea. These findings may provide a basis for clarifying the pathogenesis of acne rosacea and for developing strategies for its prevention and control.Key words: Rosacea; Genomics; Neuropeptides; Immunology" @default.
- W3028692357 created "2020-06-05" @default.
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- W3028692357 date "2015-01-15" @default.
- W3028692357 modified "2023-09-23" @default.
- W3028692357 title "Pathogenesis of acne rosacea: an update" @default.
- W3028692357 doi "https://doi.org/10.3760/cma.j.issn.1673-4173.2015.01.006" @default.
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