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- W3028734769 abstract "Objective: to study the prevalence of different types of human papilloma virus (HPV) in cervix and anal canal in patients with HPV-associated cervical intraepithelial neoplasia (CIN) of varying severity.Material and methods: the clinical examination, colposcopy; high resolution anoscopy; cytology; typing of HPV.Results. The study involved 204 women, mean age 30±1.2 years. By results of inspection are formed 2 groups: 1 - 92 (45%) with CIN I-III, 2 - 112 (55%) without CIN. In group 1 in the cervical canal were detected HPV 16, 68 (р<0.05), in anal region 15, 56 (р<0.05). In group 2 in the cervical canal were detected HPV 16 (21.4%), 52(19.6%), 31, 44 (12.5%), 33 (10.7%), in anal region 44 (25%), 31 (19.4%), 53, 6(13.8%), 16, 52, 11, 18 (11.1%). In patients in group 1, 1.5 times more likely was found changes of anal epithelium compared with the group 2. Abnormal anal cytology was found in 12% of patients. High risk HPV cause more severe changes in the anal epithelium similar to the cervix.Conclusion. In patients with HPV-associated diseases of anogenital region revealed differences in the types of HPV in the cervical canal and anal region. The dominant type of HPV in women with CIN in the cervix and anus is the HPV type 16. HPV-associated cervical disease, including CIN, pose a risk of infection and HPV-associated diseases of the anal region, including anal intraepithelial neoplasia." @default.
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- W3028734769 date "2016-02-15" @default.
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- W3028734769 title "Results of the study of HPV-typing of anogenital area in patients with cervical intraepithelial neoplasia" @default.
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