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- W3028792223 abstract "Four hundred and twenty-two patients were diagnosed as idiopathic thrombocytopenic purpura (ITP) in the Pediatric Department of the National Taiwan University Hospital (NTUH) from January 1961 to December 1982. After exclusion of 80 inadequate follow-up cases, and 32 known chronic (referred) cases on their first visit to this hospital, 232 cases (74.8%) were described as acute form, 69 cases (22.3%) were chronic form and nine cases (2.9%) were categorized as chronic recurrent form. The whole series showed no sex predilection, but there was some female predominance in the chronic form. Sixty-seven percent of our cases occurred before six years of age. The disease occurred more frequently in summer and autumn. Distribution of initial platelet counts was almost the same in both acute and chronic forms. Clinical manifestations were petechiae and/or ecchymosis over the skin (94.1%), epistaxis (39.3%), oral mucosal bleeding (31.3%), G-I bleeding (7.8%) and hematuria (3.8%). Intracranial hemorrhage occurred in 1.2% of the cases. Forty-two per cent of the cases had obvious antecedent disease such as upper respiratory infection, fever, rubella, measles, et cetera. Of the acute form, 84.9% of the cases recovered within six weeks. In chronic cases, 23 cases received splenectomy, with an overall response rate of 56.5%. Females had twice the success rate of males. There was no operation mortality. Female sex and older age were the predictable factors for better response in this series." @default.
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- W3028792223 date "1985-01-01" @default.
- W3028792223 modified "2023-09-24" @default.
- W3028792223 title "A clinical study of childhood idiopathic thrombocytopenic purpura" @default.
- W3028792223 hasPublicationYear "1985" @default.
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