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- W3028793500 abstract "Objective To observe the effect of Rho kinase inhibitor (fasudil) on pulmonary hypertension patients with chronic pulmonary heart disease,and investigate its mechanism.Methods Sixty patients with chronic pulmonary heart disease were randomly divided into treatment group and control group,the patients in treatment group were given fasudit injection based on regular treatment,the patients in the control group were given routine treatment.Results After treatment,compared with before treatment,SPAP and MPAP were significantly decreased of the two groups,the differences were statistically significant (P ＜ 0.01).After treatment,differences of SPAP,MPAP between the two groups were significant (P ＜ 0.05).Conclusions Rho kinase inhibitor (fasudil) can significantly reduce pulmonary hypertension of chronic pulmonary heart disease,ameliorate pulmonary vascular remodeling,and has positive significance for the treatment of patients with chronic pulmonary heart disease.Key words: Chronic pulmonary heart disease; Pulmonary hypertension; Rho kinase inhibitors" @default.
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- W3028793500 date "2014-01-10" @default.
- W3028793500 modified "2023-09-27" @default.
- W3028793500 title "Effect of Rho kinase inhibitor on pulmonary hypertension in patients with chronic pulmonary heart disease and its mechanism" @default.
- W3028793500 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2014.01.006" @default.
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