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- W3028830184 abstract "ObjectiveTo explore the changes of sacral spinal motor evoked potentials (SMEP) in male rabbit models with different degrees of sacral spinal cord ischemia in the acute phase and the correlation with sacral spinal cord pathological damage.MethodsThirty rabbits were randomly divided into 6 groups: control group (n=5), just separating lumbar artery; and 5 experimental groups (n=5 each), ligating lumbar arteries (1, 2, 3, 4 and 5). The change patterns of SMEP in male rabbits with spinal cord ischemia in the acute phase were sequentially recorded for 2 h, and the correlation with spinal cord pathological damage was analyzed.ResultsImmediatelly after ligating 2-5 lumbar arteries, the latency for SMEP prolonged and the amplitude decreased. After (0.2±0.2), (0.4±0.3), (0.3±0.2) and (0.4±0.2) min, the SMEP was stable. The volatility change of SMEP was stabilized at (94.5±5.9)%, (51.6±30.6)%, (9.6±11.0)% and (0.0±0.0)% respectively (P<0.05). After ligating 2-5 lumbar arteries, the latency was significantly prolonged as compared with control group and that before ligation (P<0.05). There was a positive correlation between the volatility change of SMEP and the spinal cord pathological damage after ligation for 2 days (r=0.939, P<0.01).ConclusionThe SMEP wave is sensitive to the ischemic injury of sacral cord. The changes of SMEP amplitude can reflect the degree of pathological damage of the sacral cord.Key words: Spinal motor evoked potentials; Spinal cord ischemia; Models, animal; Rabbits" @default.
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- W3028830184 date "2016-12-08" @default.
- W3028830184 modified "2023-10-06" @default.
- W3028830184 title "Changes of spinal motor evoked potentials in the acute phase of spinal cord ischemia injury in male rabbits" @default.
- W3028830184 doi "https://doi.org/10.3760/cma.j.issn.1001-9030.2016.12.028" @default.
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