Matches in SemOpenAlex for { <https://semopenalex.org/work/W3028853588> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3028853588 endingPage "728" @default.
- W3028853588 startingPage "726" @default.
- W3028853588 abstract "ObjectiveTo detect the expression of β-catenin in the tissues of primary central nervous system lymphoma (PCNSL), and to discuss its function in PCNSL.MethodsThe paraffin embedded tissues from 10 patients diagnosed as PCNSL from October 2010 to April 2012 were collected as the experimental group. The paraffin embedded tissues from 10 patients with lymphadenitis were collected as the control group. Quantitative real-time PCR and immunohistochemical method were used to detect the expression of β-catenin in these tissues, and the relationships between β-catenin and clinical data were analyzed.ResultsImmunohistochemistry results showed that β-catenin protein was localized in the cytoplasm and (or) nucleus. Among 10 PCNSL patients, β-catenin protein was positive in 4 patients, while it was no positive in all of 10 lymphadenitis patients, with the significant differences between both groups (P < 0.05). The β-catenin gene relative expression level was 4.70 ± 0.57 and 1.00 ± 0.27 in the experimental group and the control group, respectively. β-catenin expression was no correlation to age, PS score, cerebrospinal fluid protein level and serum lactate dehydrogenase level of patients with PCNSL.ConclusionsWhether in mRNA level or in protein level, β-catenin expression is always high in PCNSL tissues, and its protein is expressed in the cytoplasm, however, this phenomenon was not observed in the tissue of lymphadenitis.Key words: Central nervous system neoplasms; Lymphoma; Gene, beta-catenin" @default.
- W3028853588 created "2020-06-05" @default.
- W3028853588 creator A5018725888 @default.
- W3028853588 creator A5021764260 @default.
- W3028853588 creator A5056905255 @default.
- W3028853588 creator A5080698941 @default.
- W3028853588 date "2015-12-25" @default.
- W3028853588 modified "2023-09-28" @default.
- W3028853588 title "Expression and significance of β-catenin gene in the tissue of primary central nervous system lymphoma" @default.
- W3028853588 doi "https://doi.org/10.3760/cma.j.issn.1009-9921.2015.12.005" @default.
- W3028853588 hasPublicationYear "2015" @default.
- W3028853588 type Work @default.
- W3028853588 sameAs 3028853588 @default.
- W3028853588 citedByCount "0" @default.
- W3028853588 crossrefType "journal-article" @default.
- W3028853588 hasAuthorship W3028853588A5018725888 @default.
- W3028853588 hasAuthorship W3028853588A5021764260 @default.
- W3028853588 hasAuthorship W3028853588A5056905255 @default.
- W3028853588 hasAuthorship W3028853588A5080698941 @default.
- W3028853588 hasConcept C104317684 @default.
- W3028853588 hasConcept C126322002 @default.
- W3028853588 hasConcept C137620995 @default.
- W3028853588 hasConcept C142724271 @default.
- W3028853588 hasConcept C150194340 @default.
- W3028853588 hasConcept C190062978 @default.
- W3028853588 hasConcept C204232928 @default.
- W3028853588 hasConcept C2779338263 @default.
- W3028853588 hasConcept C2781173314 @default.
- W3028853588 hasConcept C30145163 @default.
- W3028853588 hasConcept C529278444 @default.
- W3028853588 hasConcept C55493867 @default.
- W3028853588 hasConcept C63363279 @default.
- W3028853588 hasConcept C71924100 @default.
- W3028853588 hasConcept C86803240 @default.
- W3028853588 hasConceptScore W3028853588C104317684 @default.
- W3028853588 hasConceptScore W3028853588C126322002 @default.
- W3028853588 hasConceptScore W3028853588C137620995 @default.
- W3028853588 hasConceptScore W3028853588C142724271 @default.
- W3028853588 hasConceptScore W3028853588C150194340 @default.
- W3028853588 hasConceptScore W3028853588C190062978 @default.
- W3028853588 hasConceptScore W3028853588C204232928 @default.
- W3028853588 hasConceptScore W3028853588C2779338263 @default.
- W3028853588 hasConceptScore W3028853588C2781173314 @default.
- W3028853588 hasConceptScore W3028853588C30145163 @default.
- W3028853588 hasConceptScore W3028853588C529278444 @default.
- W3028853588 hasConceptScore W3028853588C55493867 @default.
- W3028853588 hasConceptScore W3028853588C63363279 @default.
- W3028853588 hasConceptScore W3028853588C71924100 @default.
- W3028853588 hasConceptScore W3028853588C86803240 @default.
- W3028853588 hasIssue "12" @default.
- W3028853588 hasLocation W30288535881 @default.
- W3028853588 hasOpenAccess W3028853588 @default.
- W3028853588 hasPrimaryLocation W30288535881 @default.
- W3028853588 hasRelatedWork W1623327531 @default.
- W3028853588 hasRelatedWork W2066223074 @default.
- W3028853588 hasRelatedWork W2152752097 @default.
- W3028853588 hasRelatedWork W2164690305 @default.
- W3028853588 hasRelatedWork W2165641356 @default.
- W3028853588 hasRelatedWork W2352281665 @default.
- W3028853588 hasRelatedWork W2357103691 @default.
- W3028853588 hasRelatedWork W2359478384 @default.
- W3028853588 hasRelatedWork W2360395243 @default.
- W3028853588 hasRelatedWork W2361688476 @default.
- W3028853588 hasRelatedWork W2364510995 @default.
- W3028853588 hasRelatedWork W2389243911 @default.
- W3028853588 hasRelatedWork W2389551003 @default.
- W3028853588 hasRelatedWork W2390615621 @default.
- W3028853588 hasRelatedWork W2391833080 @default.
- W3028853588 hasRelatedWork W2394610681 @default.
- W3028853588 hasRelatedWork W2415422379 @default.
- W3028853588 hasRelatedWork W3030014506 @default.
- W3028853588 hasRelatedWork W3147740749 @default.
- W3028853588 hasRelatedWork W914986810 @default.
- W3028853588 hasVolume "24" @default.
- W3028853588 isParatext "false" @default.
- W3028853588 isRetracted "false" @default.
- W3028853588 magId "3028853588" @default.
- W3028853588 workType "article" @default.