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- W3028862017 abstract "目的 探讨慢性心力衰竭(CCF)患者血清基质金属蛋白酶-2、9(MMP-2、MMP-9)的变化及其临床意义.方法 测定60例CCF患者及50名正常对照者MMP-2、MMP-9水平,用超声心动仪测定两组患者心脏结构和功能指标,分析血清MMP-2、MMP-9与CCF的关系.结果 CCF患者血清MMP-2、MMP-9水平明显高于对照者(P＜0.05);左室收缩末内径、左室舒张末内径、左室收缩末期容积和舒张末期容积随着CCF病情加重而增大(P＜0.05),左心室射血分数随着CCF病情加重而降低(P＜0.05).结论 MMP-2、MMP-9共同参与了CCF的发生、发展,可作为反映心室重塑和心功能恶化的有效指标。" @default.
- W3028862017 created "2020-06-05" @default.
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- W3028862017 date "2007-07-28" @default.
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- W3028862017 title "Changes and clinical significance of serum matrix metalloproteinase in patients with chronic cardiac failure" @default.
- W3028862017 doi "https://doi.org/10.3760/cma.j.issn.1008-6706.2007.07.008" @default.
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