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- W3028864039 startingPage "113" @default.
- W3028864039 abstract "转基因诱导移植耐受、防止移植物排斥的研究，近年来有了较大进展。转MHC基因诱导移植耐受是一多种机制参与的过程。封闭T细胞活化的共刺激信号诱导耐受应用最多的是转CTLA4-Ig基因，其表达产物可与CD28分子竞争性结合B7分子，从而阻断T细胞活化的第二信号。转抑制性细胞因子基因诱导移植耐受，应用最广的是IL-10、TGFβ1，其机制是利用该类因子的免疫抑制活性，调节Th1／Th2的平衡。转FasL基因主要是诱导免疫细胞凋亡，其诱导效果的可靠性有待于探讨。" @default.
- W3028864039 created "2020-06-05" @default.
- W3028864039 creator A5029356050 @default.
- W3028864039 date "2002-05-05" @default.
- W3028864039 modified "2023-09-25" @default.
- W3028864039 title "043 转基因诱导移植耐受的研究进展" @default.
- W3028864039 doi "https://doi.org/10.3760/cma.j.issn.1673-4394.2002.03.001" @default.
- W3028864039 hasPublicationYear "2002" @default.
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