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- W3028889506 abstract "目的 研究白内障早期患者总高阶像差、各分阶像差的变化、相互间的相关性及其与C6～C27项Zernike系数间的相关性,探讨其在白内障早期诊断中的作用.方法 选取白内障早期患者22例30眼,设为A组.正常对照组24例30眼,设为B组.使用Wavelight波阵面像差仪进行分析得到3至6阶像差均方根值(root mean square,RMS3～RMS6)和总高阶像差均方根值(RMSh)以及C6～C27项Zernike系数.结果 ①波阵面像差检测结果:A组的RMSh、RMS3～RMS6较B组明显增高,两组各项值的比较有显著性差异(P=0.000).②两组间的相关性:B组中,RMS3～RMS6之间仅表现在RMS4与RMS5(r=0.587,P=0.001)有相关性,以及RMSh与RMS3、RMS4、RMS6(r=0.420～0.723,P＜0.05)有相关性;而A组RMSh及RMS3～RMS6彼此间密切相关(r=0.569～0.980,P＜0.01).③两组RMS3～RMS6与C6～C27间的相关性:A组RMS3与C9呈正相关(r=0.421,P=0.020),RMS4与C10～C14无相关性;而B组RMS3与C8呈负相关(r=-0.478,P=0.008),RMS4与C12、C14呈正相关(r=0.641,0.514;P=0.000,0.004).结论 ①白内障早期患者的RMSh及RMS3～RMS6均较正常人显著增加,导致视觉质量的下降,可以解释患者的视物模糊等主观症状.②白内障早期患者由于晶状体混浊使得RMSh与RMS3～RMS6及RMS3～RMS6各项之间密切相关,这一点可作为辅助白内障早期诊断的参考依据之一.③白内障早期患者的RMS3与C9呈正相关,RMS4与C10～C14无相关性;而正常人的RMS3与C8呈负相关,RMS4与C12、C14呈正相关,白内障早期患者丧失了原有的相关性而建立了新的相关性,为白内障早期诊断提供了另一参考依据。" @default.
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- W3028889506 date "2006-10-31" @default.
- W3028889506 modified "2023-09-25" @default.
- W3028889506 title "The application of wavefront abberation analysis in the early diagnosis of cataract" @default.
- W3028889506 doi "https://doi.org/10.3760/cma.j.issn.1008-1801.2006.05.014" @default.
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