Matches in SemOpenAlex for { <https://semopenalex.org/work/W3028909060> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3028909060 endingPage "314" @default.
- W3028909060 startingPage "312" @default.
- W3028909060 abstract "Objective To determine the effects of hypoxia inducible factor-1α(HIF-1α) expression on postoperative adjuvant radiotherapy in esophageal carcinoma. Methods 95 cases with esophageal carcinoms who received radical operation were analyzed with followed-up data from 1995 to 1998.Expression of HIF-1α in 45 patients with esophageal carcinoma who received radiotherapy after radical operation were deternlined by immunohistochemical method in contrast with 50 patients with esophageal carcinoma received surgery alone.Kaplan-Meier method and COX proportional hazard model were used to analyze.Results The positive expression of HIF-1α in esophageal carcinoma was observed mainly in the nucleus of tumor cells.The positive expression rate of HIF-1α in esophageal carcinoma was 58.9%.The expression of HIF-1α had no relationship with age,sex,histologic subtype and T stage,but had positive relationship with recurrence and distant metastasis.There was significant difference between patients with positive and negative HIF-1α protein expression in surgery alone and postoperation radiotherapy group. COX model analysis showed that HIF-1α had separate and significant impacts on prognosis in surgery group and surgery plus radiotherapy group. Conclusion Over expression of HIF-1α protein suggests a poor prognosis,and has tendency to resist radiotherapy in esophageal carcinoma.Key words: Esophageal neoplasms; HIF-1α; Radiotherapy,computer-assisted; Adjuant radiotherapy; Prognosis" @default.
- W3028909060 created "2020-06-05" @default.
- W3028909060 creator A5017270428 @default.
- W3028909060 creator A5029214510 @default.
- W3028909060 creator A5064422431 @default.
- W3028909060 date "2010-05-28" @default.
- W3028909060 modified "2023-09-24" @default.
- W3028909060 title "Clinical significance of hypoxia inducible factor-1α expression on postoperative adjuvant radiotherapy in esophageal carcinoma" @default.
- W3028909060 doi "https://doi.org/10.3760/cma.j.issn.1006-9801.2010.05.009" @default.
- W3028909060 hasPublicationYear "2010" @default.
- W3028909060 type Work @default.
- W3028909060 sameAs 3028909060 @default.
- W3028909060 citedByCount "0" @default.
- W3028909060 crossrefType "journal-article" @default.
- W3028909060 hasAuthorship W3028909060A5017270428 @default.
- W3028909060 hasAuthorship W3028909060A5029214510 @default.
- W3028909060 hasAuthorship W3028909060A5064422431 @default.
- W3028909060 hasConcept C10515644 @default.
- W3028909060 hasConcept C126322002 @default.
- W3028909060 hasConcept C143998085 @default.
- W3028909060 hasConcept C146357865 @default.
- W3028909060 hasConcept C151730666 @default.
- W3028909060 hasConcept C178790620 @default.
- W3028909060 hasConcept C185592680 @default.
- W3028909060 hasConcept C204232928 @default.
- W3028909060 hasConcept C2776283816 @default.
- W3028909060 hasConcept C2777546739 @default.
- W3028909060 hasConcept C50382708 @default.
- W3028909060 hasConcept C509974204 @default.
- W3028909060 hasConcept C540031477 @default.
- W3028909060 hasConcept C71924100 @default.
- W3028909060 hasConcept C7836513 @default.
- W3028909060 hasConcept C86803240 @default.
- W3028909060 hasConceptScore W3028909060C10515644 @default.
- W3028909060 hasConceptScore W3028909060C126322002 @default.
- W3028909060 hasConceptScore W3028909060C143998085 @default.
- W3028909060 hasConceptScore W3028909060C146357865 @default.
- W3028909060 hasConceptScore W3028909060C151730666 @default.
- W3028909060 hasConceptScore W3028909060C178790620 @default.
- W3028909060 hasConceptScore W3028909060C185592680 @default.
- W3028909060 hasConceptScore W3028909060C204232928 @default.
- W3028909060 hasConceptScore W3028909060C2776283816 @default.
- W3028909060 hasConceptScore W3028909060C2777546739 @default.
- W3028909060 hasConceptScore W3028909060C50382708 @default.
- W3028909060 hasConceptScore W3028909060C509974204 @default.
- W3028909060 hasConceptScore W3028909060C540031477 @default.
- W3028909060 hasConceptScore W3028909060C71924100 @default.
- W3028909060 hasConceptScore W3028909060C7836513 @default.
- W3028909060 hasConceptScore W3028909060C86803240 @default.
- W3028909060 hasIssue "05" @default.
- W3028909060 hasLocation W30289090601 @default.
- W3028909060 hasOpenAccess W3028909060 @default.
- W3028909060 hasPrimaryLocation W30289090601 @default.
- W3028909060 hasRelatedWork W189957930 @default.
- W3028909060 hasRelatedWork W1973787395 @default.
- W3028909060 hasRelatedWork W1990544952 @default.
- W3028909060 hasRelatedWork W2028529888 @default.
- W3028909060 hasRelatedWork W2042469467 @default.
- W3028909060 hasRelatedWork W2047752558 @default.
- W3028909060 hasRelatedWork W2061110949 @default.
- W3028909060 hasRelatedWork W2076458910 @default.
- W3028909060 hasRelatedWork W2085916016 @default.
- W3028909060 hasRelatedWork W2146145587 @default.
- W3028909060 hasRelatedWork W2316591550 @default.
- W3028909060 hasRelatedWork W2360575239 @default.
- W3028909060 hasRelatedWork W2360818721 @default.
- W3028909060 hasRelatedWork W2386261206 @default.
- W3028909060 hasRelatedWork W2601651411 @default.
- W3028909060 hasRelatedWork W2900501701 @default.
- W3028909060 hasRelatedWork W2906000951 @default.
- W3028909060 hasRelatedWork W2990089687 @default.
- W3028909060 hasRelatedWork W3022200123 @default.
- W3028909060 hasRelatedWork W385154357 @default.
- W3028909060 hasVolume "22" @default.
- W3028909060 isParatext "false" @default.
- W3028909060 isRetracted "false" @default.
- W3028909060 magId "3028909060" @default.
- W3028909060 workType "article" @default.