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- W3028930115 abstract "目的 探讨细胞间黏附分子-1(ICAM-1)、基质金属蛋白酶-9(MMP-9)在人脑胶质瘤的表达及相关性研究.方法采用免疫组织化学法检测82例胶质瘤组织中ICAM-1、MMP-9的表达水平.结果ICAM-1在82例人脑胶质瘤蜡块组织中全部呈阳性表达,72例MMP-9呈阳性表达,阳性率87.80%,实验对照为脑外伤手术减压的脑组织11例未见ICAM-1、MMP-9表达.ICAM-1、MMP-9阳性表达水平在胶质瘤高度恶性组高于低度恶性组,差别有显著性意义(P＜0.01).ICAM-1和MMP-9在人脑胶质瘤的表达存在相关性(r=0.436).结论ICAM-1和MMP-9在胶质瘤存在协同作用,共同参与胶质瘤的发生、发展和恶性演变,并由此推测ICAM-1与MMP-9联合检测会更好地对脑胶质瘤的恶性生物学行为进行评价和判断。" @default.
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- W3028930115 date "2005-09-15" @default.
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- W3028930115 title "Study on expression and correlation between ICAM-1 and MMP-9 in human glioma" @default.
- W3028930115 doi "https://doi.org/10.3760/cma.j.issn.1671-8925.2005.09.014" @default.
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