Matches in SemOpenAlex for { <https://semopenalex.org/work/W3028931404> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3028931404 endingPage "657" @default.
- W3028931404 startingPage "653" @default.
- W3028931404 abstract "Objective To investigate the effect of exogenous insulin-like growth factor-1(IGF-1)on growth of gastric smooth muscle cells(SMCs)and synthesis of stem cell factor(SCF).Methods Gastric SMCs were cultured by enzymolysis and were identified by α-actin immunocytochemical method.After that,SMCs were incubated with different concentrations of IGF-1(0,50,100,150μg/L)or IGF-1 receptor monoclonal antibody(0.50,100,150μg/L)for 24 hours.Proliferation of SMCs was measured by MTT.The expressions of SCF protein and RNA were analyzed by Western blotting and quantitative reverse transcription-polymerase chain reaction,respectively.The SCF content in the culture fluid was detected by enzyme-linked immunosorbent assay(ELISA).Results The proliferation of gastric SMCs and the expression of SCF can be enhanced by IGF-1,and 100μg/L of IGF-1 may be the final effective concentration.Nevertheless,these could be inhibited by IGF-1 receptor monoclonal antibody in a dose-dependent manner.ConclusionElevated expression of SCF may be induced by IGF-1 through proliferation of SMC.Key words: Insulin-like growth factor-1; Myocytes,smooth muscle; Stem cell factor Antibodies" @default.
- W3028931404 created "2020-06-05" @default.
- W3028931404 creator A5004368692 @default.
- W3028931404 creator A5015860750 @default.
- W3028931404 creator A5030357379 @default.
- W3028931404 creator A5031172404 @default.
- W3028931404 creator A5064024990 @default.
- W3028931404 creator A5082736240 @default.
- W3028931404 date "2009-10-15" @default.
- W3028931404 modified "2023-09-28" @default.
- W3028931404 title "Effects of insulin-like growth factor-1 on expression of stem cell factor in gastric smooth muscle cells" @default.
- W3028931404 doi "https://doi.org/10.3760/cma.j.issn.0254-1432.2009.10.002" @default.
- W3028931404 hasPublicationYear "2009" @default.
- W3028931404 type Work @default.
- W3028931404 sameAs 3028931404 @default.
- W3028931404 citedByCount "0" @default.
- W3028931404 crossrefType "journal-article" @default.
- W3028931404 hasAuthorship W3028931404A5004368692 @default.
- W3028931404 hasAuthorship W3028931404A5015860750 @default.
- W3028931404 hasAuthorship W3028931404A5030357379 @default.
- W3028931404 hasAuthorship W3028931404A5031172404 @default.
- W3028931404 hasAuthorship W3028931404A5064024990 @default.
- W3028931404 hasAuthorship W3028931404A5082736240 @default.
- W3028931404 hasConcept C104317684 @default.
- W3028931404 hasConcept C109159458 @default.
- W3028931404 hasConcept C134018914 @default.
- W3028931404 hasConcept C153911025 @default.
- W3028931404 hasConcept C159654299 @default.
- W3028931404 hasConcept C170493617 @default.
- W3028931404 hasConcept C185592680 @default.
- W3028931404 hasConcept C2022786 @default.
- W3028931404 hasConcept C203014093 @default.
- W3028931404 hasConcept C207200792 @default.
- W3028931404 hasConcept C2775960820 @default.
- W3028931404 hasConcept C2780689927 @default.
- W3028931404 hasConcept C2780783641 @default.
- W3028931404 hasConcept C28328180 @default.
- W3028931404 hasConcept C2908605954 @default.
- W3028931404 hasConcept C542903549 @default.
- W3028931404 hasConcept C54355233 @default.
- W3028931404 hasConcept C55493867 @default.
- W3028931404 hasConcept C62112901 @default.
- W3028931404 hasConcept C81885089 @default.
- W3028931404 hasConcept C85265743 @default.
- W3028931404 hasConcept C86803240 @default.
- W3028931404 hasConcept C95444343 @default.
- W3028931404 hasConceptScore W3028931404C104317684 @default.
- W3028931404 hasConceptScore W3028931404C109159458 @default.
- W3028931404 hasConceptScore W3028931404C134018914 @default.
- W3028931404 hasConceptScore W3028931404C153911025 @default.
- W3028931404 hasConceptScore W3028931404C159654299 @default.
- W3028931404 hasConceptScore W3028931404C170493617 @default.
- W3028931404 hasConceptScore W3028931404C185592680 @default.
- W3028931404 hasConceptScore W3028931404C2022786 @default.
- W3028931404 hasConceptScore W3028931404C203014093 @default.
- W3028931404 hasConceptScore W3028931404C207200792 @default.
- W3028931404 hasConceptScore W3028931404C2775960820 @default.
- W3028931404 hasConceptScore W3028931404C2780689927 @default.
- W3028931404 hasConceptScore W3028931404C2780783641 @default.
- W3028931404 hasConceptScore W3028931404C28328180 @default.
- W3028931404 hasConceptScore W3028931404C2908605954 @default.
- W3028931404 hasConceptScore W3028931404C542903549 @default.
- W3028931404 hasConceptScore W3028931404C54355233 @default.
- W3028931404 hasConceptScore W3028931404C55493867 @default.
- W3028931404 hasConceptScore W3028931404C62112901 @default.
- W3028931404 hasConceptScore W3028931404C81885089 @default.
- W3028931404 hasConceptScore W3028931404C85265743 @default.
- W3028931404 hasConceptScore W3028931404C86803240 @default.
- W3028931404 hasConceptScore W3028931404C95444343 @default.
- W3028931404 hasIssue "10" @default.
- W3028931404 hasLocation W30289314041 @default.
- W3028931404 hasOpenAccess W3028931404 @default.
- W3028931404 hasPrimaryLocation W30289314041 @default.
- W3028931404 hasRelatedWork W1557003501 @default.
- W3028931404 hasRelatedWork W1833656894 @default.
- W3028931404 hasRelatedWork W1971034762 @default.
- W3028931404 hasRelatedWork W1971118654 @default.
- W3028931404 hasRelatedWork W2005575410 @default.
- W3028931404 hasRelatedWork W2009431295 @default.
- W3028931404 hasRelatedWork W2041095491 @default.
- W3028931404 hasRelatedWork W2044814271 @default.
- W3028931404 hasRelatedWork W2075671215 @default.
- W3028931404 hasRelatedWork W2076014957 @default.
- W3028931404 hasRelatedWork W2088007215 @default.
- W3028931404 hasRelatedWork W2106648038 @default.
- W3028931404 hasRelatedWork W2129457436 @default.
- W3028931404 hasRelatedWork W2154755621 @default.
- W3028931404 hasRelatedWork W2163006935 @default.
- W3028931404 hasRelatedWork W2414734379 @default.
- W3028931404 hasRelatedWork W2416550682 @default.
- W3028931404 hasRelatedWork W2423338149 @default.
- W3028931404 hasRelatedWork W2617650361 @default.
- W3028931404 hasRelatedWork W3144355284 @default.
- W3028931404 hasVolume "29" @default.
- W3028931404 isParatext "false" @default.
- W3028931404 isRetracted "false" @default.
- W3028931404 magId "3028931404" @default.
- W3028931404 workType "article" @default.