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• W3028931645 abstract "目的 探讨膦甲酸钠联合阿德福韦酯治疗慢性重型乙型肝炎的疗效.方法 将123例慢性乙型重型肝炎患者随机分为对照组61例,给予治疗常规治疗加拉米夫定100 mg,1次/d;治疗组62例,在常规治疗基础上加用膦甲酸钠和阿德福韦酯,膦甲酸钠注射液3.0 g 250 ml,静脉滴注,2次/d,阿德福韦酯胶囊10 mg,1次/d,疗程28 d.结果 肝功能复常率、HBV-DNA的阴转率治疗组优于对照组(P＜0.001).治疗组肝性脑病、感染、肝肾综合征发生率分别为20.9%(13/62)、19.4%(12/62)、17.7%(11/62)明显低于对照组41.0%(25/61)、39.3%(24/61)、37.7%(23/61)差异有统计学意义(P＜0.05).病死率:治疗组22.6%(14/62),显著低于对照组54.1%(33/61)(P＜0.01).结论 在基础保肝支持治疗同时,及时应用膦甲酸钠联合阿德福韦酯胶囊能显著提高慢性乙型重型肝炎的抢救成功率。" @default.
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• W3028931645 date "2009-01-25" @default.
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• W3028931645 title "Foscarnet sodium and adefovir dipivoxil for treatment of 62 patients with chronic severe hepatitis B" @default.
• W3028931645 doi "https://doi.org/10.3760/cma.j.issn.1673-8799.2009.01.012" @default.
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