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- W3028996811 abstract "Gene therapy is one of the most effective methods to some refractory diseases such as cancer and he-reditary diseases. However, the limits existing in transgenosis has become the biggest barrier for the extensiveapplication of gene therapy. HIV-1 (human immunodeficiency virus type 1 )-based leativiral vectors can trans-duce dividing or nondividing cells and can stably integrate into their targets for long-term expression. Accord-ingly, HIV-1-based lentiviral vectors are novel vectors with potential application in the induction of immune re-sponses, inhibition of tumor growth and induction of the immue tolerance to allogrofts.Key words: Lentiviral vector; HIV-1 ; Gene immunotherapy" @default.
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- W3028996811 date "2008-09-05" @default.
- W3028996811 modified "2023-09-22" @default.
- W3028996811 title "Progression and application of HIV-1-derived lentivectors" @default.
- W3028996811 doi "https://doi.org/10.3760/cma.j.issn.1673-4394.2008.05.006" @default.
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