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- W3029014734 abstract "ObjectiveTo evaluate the effects of interferon therapy after curative surgical intervention on improving prognosis of patients with hepatitis C-related hepatocellular carcinoma (HCC).MethodsWe searched randomized clinical trials from 1990 to 2015 on interferon therapy after curative surgical intervention in patients with hepatitis C-related HCC from the Cochrane Library, the Cochrane Database of Systematic Reviews, MEDLINE and Embase. A Meta-analysis was carried out using Revman 5.ResultsThere were 7 studies included in this research. The results showed that interferon therapy after curative surgical intervention in patients with hepatitis C-related HCC reduced the recurrence rate of HCC at 3 years (RR=0.84, 95%CI 0.73~0.97, P 0.05). Stratified subgroup analyses showed interferon therapy after liver resection reduced the recurrence rate (RR=0.62, 95%CI 0.39~1.00, P=0.05). For patients with tumors less than 3 cm, interferon therapy reduced the recurrence rate (RR=0.82, 95%CI 0.69~0.98, P<0.05).ConclusionInterferon therapy after curative surgical intervention improved prognosis in patients with hepatitis C-related HCC.Key words: Hepatitis C virus; Hepatocellular carcinoma; Interferon; Recurrence" @default.
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- W3029014734 date "2016-12-28" @default.
- W3029014734 modified "2023-09-27" @default.
- W3029014734 title "Interferon therapy after curative surgical intervention to improve prognosis in patients with hepatitis C-related hepatocellular carcinoma: a Meta-analysis" @default.
- W3029014734 doi "https://doi.org/10.3760/cma.j.issn.1007-8118.2016.12.004" @default.
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