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- W3029109948 abstract "ObjectiveTo discuss the safety and effectiveness of fiberoptic bronchoscopy assisted by noninvasive ventilation in critical patients.MethodsThirty patients with oxygenation index<200 mmHg who required bronchoscopy were entered into the study.Procedures including bronchoalveolar lavage, protective cell brushing, endobronchial biopsy and others were performed if needed.The patients were randomly divided into noninvasive ventilation group (n=15) and venturi mask group (n=15). The primary end points were changes in the oxygenation index, vital signs during bronchoscopy, and the intubation rate within the one hour and 24 hours after terminating the procedure.ResultsThere was no statistical significance in sex, age, vital signs, APACHEⅡ score between the two groups.During bronchoscopy, oxygenation index increased from (151.20±21.63) mmHg to (177.67±18.46) mmHg (t=-3.605, P=0.001) in the noninvasive ventilation group, and decreased by 15.7% in the venturi mask group, from (158.53±21.37) mmHg to (133.60±17.79) mmHg (t=3.473, P=0.002). The heart rate in the venturi mask group was faster.One patient in the venturi mask group needed endotracheal intubation.All the three patients with cancer were definitely diagnosed.Major bacteria isolated included Pseudomonas aeruginosa and Klebsiella pneumoniae.ConclusionsIn patients with severe respiratory failure, fiberoptic bronchoscopy assisted by noninvasive ventilation is superior to conventional oxygen supplementation with more stable oxygenation index, vital signs, and better security.Key words: Noninvasive ventilation; Fiberoptic bronchoscopy; Critical patients" @default.
- W3029109948 created "2020-06-05" @default.
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- W3029109948 date "2019-07-05" @default.
- W3029109948 modified "2023-09-23" @default.
- W3029109948 title "Application of fiberoptic bronchoscopy assisted by noninvasive ventilation in critical patients" @default.
- W3029109948 doi "https://doi.org/10.3760/cma.j.issn.1673-436x.2019.13.004" @default.
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