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- W3029120375 abstract "Objective The characteristic of PET/CT imaging in patients with multiple myeloma (MM)were investigated.The aim of this study was to assess the adequacy of PET/CT in staging of MM pa-tients. Methods Fifteen newly diagnosed patients with MM underwent 18F-fluomdeoxyglucose (FDG) PET/CT examination before treatment.Plasma cell pathology Was Confirmed by bone marrow biopsy and (or)excisonal histopathology. Quantification test of monoclonal gammopathie protein (IgG>35g/I) Was elevated in 9 cases,and 24 h urine Bence-Jones protein Was positive in 8 eases(>1g).Osteolytic bone lesions were shown on CT scan in all patients and clinical diagnosis Was established according to the stand-ard of WHO(2001).Results A total 137 lesions were detected on PET/CT study.Among them.51 le-sions Was located in skull(37.2%),36 in rib(26.3%),17 in centrum(12.4%).10 in ilium (7.3%),8 in sacrum(5.8%),6 in limbs(4.4%),5 in clavicle(3.6%)and 4 in scapula(2.9%).According to PET/CT results.high 18F-FDG uptake Was found in 71 lesions with positive detection rate of 51.8%(7l/137),whereas other 66 lesions with low or hypometabolic 18F.FDG uptake.On CT imaging,typical findings were multiple lyric bone destructions and numerous punched-out defected without surround-ing sclerosis.Conclusion PET/CT imaging may be useful in MM staging. Key words: Multiple myeloma; Tomography,emission-computed; Tomography,X-ray computed; Deoxyglucose" @default.
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- W3029120375 date "2009-04-25" @default.
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- W3029120375 title "The staging value with PET/CT imaging in multiple myeloma" @default.
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