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- W3029207747 abstract "Objective To investigate the relationship between the 6-Keto-PGF1α,TXB2 and the endotheliosis and thrombosis of the new endomembrance on the prostheses seeded by CD34 stem cells.Method Twelve dogs were evenly divided into two groups; ePTFE prostheses and weaved Dacron prostheses implanted into the abdominal aorta(AA) and inferior vena cava (IVC).in each group, 4 dogs were implanted by prostheses seeded by CD34+ stem cells, 2 dogs were implanted prostheses treated by autogenous blood only as control.The peripheral blood was collected in preoperative and 3 ,7,14,30,60 days postoperation.light and electron microscopy were applied to observe the endotheliosis and thrombosis of the new endomembrance when harvesting all the prostheses in the 60 days.Result The platelet, 6-Keto-PG F1α,TXB2 and P/T in experimental group was significantly different compared with control group.The new endomembrane in control group was significantly thickener than the experimental group.Conclusions CD34+ stem cell inhibits PGF1α and P/T ratio decrease, restrains TXB2 and platelet excessively rise, prevents intimal hyperplasia and thrombosis in a CD34+ stem cells seeded blood vessel prostheses.Key words: Stem cell transplantation; Blood vessel prosthesis; Antigens, CD34; Prostacyclin; Thromboxane B2" @default.
- W3029207747 created "2020-06-05" @default.
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- W3029207747 date "2011-05-25" @default.
- W3029207747 modified "2023-09-23" @default.
- W3029207747 title "The changes of serum 6-k-PGF1α and TXB2 levels in dog's blood vessel prostheses seeded with CD34+ stem cells" @default.
- W3029207747 doi "https://doi.org/10.3760/cma.j.issn.1007-631x.2011.05.020" @default.
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