FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029263929> ?p ?o ?g. }

• W3029263929 endingPage "A341" @default.
• W3029263929 startingPage "A341" @default.
• W3029263929 abstract "Abstract Introduction In typically developing youth, increases in body mass index (BMI) and rates of obesity accompany treatment of obstructive sleep apnea syndrome (OSAS) with adenotonsillectomy regardless of baseline BMI and OSAS severity. Residual OSAS following adenotonsillectomy and overweight/obesity are common in Down syndrome (DS). We sought to examine the impact of positive airway pressure (PAP) on BMIZ in youth with DS and OSAS. Methods Baseline, 6, and 12 month height/length and weight as well as pre-PAP PSG data were abstracted from the Children’s Hospital of Philadelphia Sleep Center for patients with DS and OSAS initiated on PAP between 01/01/2014-07/11/01/2017 (N=73; Median age=6.6y IQR: 3.6-12.1; 52% White, 29% Black; 42% Male). BMIZ was calculated. Longitudinal mixed effects models adjusted for adherence from 0-6 months, baseline BMIZ, and baseline SpO2 nadir were used to evaluate change in BMIZ at months 6 and 12 and the impact of baseline BMIZ on trajectories. Results OAHI (median; IQR) at initiation was 15.9 (8.1-28.9) events/hour, SpO2 nadir was 83% (77-88), and BMIZ was 1.50 (0.94-2.34). No differences in BMIZ at 6 and 12 months compared to baseline BMIZ were found (p&gt;0.2 for both). Baseline BMIZ was associated with BMIZ at 6- and 12 months (β-coefficient=0.99; p&lt;0.0001); the increase in BMIZ at 12 mo (β-coefficient= 0.49, p=0.001) was offset with decreasing BMIZ (12mo*baseline BMIZ β-coefficient= -0.3; p&lt;0.0001); such that lower BMIZ was associated with increases in BMIZ while higher BMIZ was associated with decreases in BMIZ. Conclusion Initiation of PAP has a beneficial impact on nutritional status in youth with DS and OSAS. In youth who are at the lower end of BMIZ, BMIZ increases to a healthier status following the initiation of PAP, and in youth who are at the higher side of BMIZ, BMIZ decreases to a healthier status. Prospective studies are needed to elaborate on these associations. Support None" @default.
• W3029263929 created "2020-06-05" @default.
• W3029263929 creator A5010497044 @default.
• W3029263929 creator A5015941407 @default.
• W3029263929 creator A5058187980 @default.
• W3029263929 creator A5066935733 @default.
• W3029263929 creator A5087836147 @default.
• W3029263929 date "2020-04-01" @default.
• W3029263929 modified "2023-09-23" @default.
• W3029263929 title "0896 Nutritional Status Improves Following The Implementation Of Positive Airway Pressure For The Treatment Of Obstructive Sleep Apnea In Youth With Down Syndrome" @default.
• W3029263929 doi "https://doi.org/10.1093/sleep/zsaa056.892" @default.
• W3029263929 hasPublicationYear "2020" @default.
• W3029263929 type Work @default.
• W3029263929 sameAs 3029263929 @default.
• W3029263929 citedByCount "0" @default.
• W3029263929 crossrefType "journal-article" @default.
• W3029263929 hasAuthorship W3029263929A5010497044 @default.
• W3029263929 hasAuthorship W3029263929A5015941407 @default.
• W3029263929 hasAuthorship W3029263929A5058187980 @default.
• W3029263929 hasAuthorship W3029263929A5066935733 @default.
• W3029263929 hasAuthorship W3029263929A5087836147 @default.
• W3029263929 hasBestOaLocation W30292639291 @default.
• W3029263929 hasConcept C126322002 @default.
• W3029263929 hasConcept C2776006263 @default.
• W3029263929 hasConcept C2778205975 @default.
• W3029263929 hasConcept C2780221984 @default.
• W3029263929 hasConcept C2780586474 @default.
• W3029263929 hasConcept C2781326671 @default.
• W3029263929 hasConcept C511355011 @default.
• W3029263929 hasConcept C71924100 @default.
• W3029263929 hasConceptScore W3029263929C126322002 @default.
• W3029263929 hasConceptScore W3029263929C2776006263 @default.
• W3029263929 hasConceptScore W3029263929C2778205975 @default.
• W3029263929 hasConceptScore W3029263929C2780221984 @default.
• W3029263929 hasConceptScore W3029263929C2780586474 @default.
• W3029263929 hasConceptScore W3029263929C2781326671 @default.
• W3029263929 hasConceptScore W3029263929C511355011 @default.
• W3029263929 hasConceptScore W3029263929C71924100 @default.
• W3029263929 hasIssue "Supplement_1" @default.
• W3029263929 hasLocation W30292639291 @default.
• W3029263929 hasOpenAccess W3029263929 @default.
• W3029263929 hasPrimaryLocation W30292639291 @default.
• W3029263929 hasRelatedWork W1866091461 @default.
• W3029263929 hasRelatedWork W2000335303 @default.
• W3029263929 hasRelatedWork W2047277250 @default.
• W3029263929 hasRelatedWork W2127131737 @default.
• W3029263929 hasRelatedWork W2326162208 @default.
• W3029263929 hasRelatedWork W2363570094 @default.
• W3029263929 hasRelatedWork W2403825624 @default.
• W3029263929 hasRelatedWork W2625095604 @default.
• W3029263929 hasRelatedWork W2777447650 @default.
• W3029263929 hasRelatedWork W3203903171 @default.
• W3029263929 hasVolume "43" @default.
• W3029263929 isParatext "false" @default.
• W3029263929 isRetracted "false" @default.
• W3029263929 magId "3029263929" @default.
• W3029263929 workType "article" @default.