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- W3029333430 abstract "ObjectiveTo evaluate the effect of propofol and sevoflurane on acute kidney function in infants undergoing pediatric parent liver transplantation.Methods80 pediatric patients scheduled for pediatric liver transplantation were randomly assigned to receive either continuous infusion of propofol or inhalation of sevoflurane. Serum creatinine (Scr), inflammatory medium and renal biomarkers were measured before surgery (T1), 30min after anhepatic phase (T2), 3h after ischemia reperfusion (T3), 36 h after surgery(T4) to evaluate the effect of anesthetics on the development of postoperative kidney injury.ResultsOverall, compared Propofol group, the mean arterial pressure changed slightly in sevoflurane group. The inflammatory factors of Scr, IL-18, TNF-α, and levels of NGAL were lower in sevoflurane group while no differences of IL-10 were found between both groups.ConclusionsCompared with propofol anesthesia, the degree of renal injury in pediatric living donor liver transplantion under sevoflurane anesthesia is reduced, which may be related to hemodynamic stability and decreased release of inflammatory factors.Key words: Pediatric liver transplantation; Sevoflurane; Acute kidney injury" @default.
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- W3029333430 date "2019-03-20" @default.
- W3029333430 modified "2023-09-28" @default.
- W3029333430 title "Effects of sevoflurame combined anesthsia on kidney function in pediatric living donor liver transplantation" @default.
- W3029333430 doi "https://doi.org/10.3760/cma.j.issn.0254-1785.2019.03.010" @default.
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