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- W3029351826 abstract "ObjectiveTo investigate the significance of c-myc gene rearrangement on the long term efficacy of diffuse large B-cell lymphoma (DLBCL), and to provide the evidence-based medicine for prognosis of DLBCL.MethodsThe Chinese and English database were searched to identify all the articles about the DLBCL with c-myc gene rearrangement by computer. Meta-analysis was completed by RevMan 5.2 software.ResultsA total of eight studies were included. The Meta-analysis results displayed that DLBCL patients with c-myc gene rearrangement had the poor prognosis. Five years progression free survival (PFS) and overall survival (OS) were significantly worse (HR= 2.28, 95% CI 1.64-3.18 and HR= 2.35, 95% CI 1.93-2.85).ConclusionC-myc gene rearrangement is a potential biomarker for the poor prognosis of DLBCL.Key words: Gene, c-myc; Lymphoma, large B-cell, diffuse; Prognosis; Meta analysis" @default.
- W3029351826 created "2020-06-05" @default.
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- W3029351826 date "2016-01-25" @default.
- W3029351826 modified "2023-09-24" @default.
- W3029351826 title "Meta analysis of prognosis in diffuse large B-cell lymphoma patients with c-myc gene rearrangement" @default.
- W3029351826 doi "https://doi.org/10.3760/cma.j.issn.1009-9921.2016.01.017" @default.
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