Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029370014> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W3029370014 endingPage "876" @default.
- W3029370014 startingPage "874" @default.
- W3029370014 abstract "Objective To investigate the effect of intravenous infusion of hyper-oxygenated solution (HOS) on small intestinal ischemia-reperfusion (I/R) injury in rabbits.Methods Twenty-four rabbits of both sexes,weighing 2.5-3.2 kg,were randomly divided into 3 groups ( n =8 each):sham operation group (group S),I/R group,and HOS group.Small intestinal I/R was produced by clamping the superior mesenteric artery (SMA) for 1 h followed by 2 h of reperfusion in I/R and HOS groups,while the SMA was only clamped in group S.HOS was infused intravenously at a rate of 20 ml· kg-1 ·h -1 via the auricular vein starting from the time immediately after clamping the SMA in group HOS and the equal volume of normal saline was infused instead of HOS in group I/R.Blood samples were obtained from the inferior vena cava at 2 h of reperfusion to detect the concentration of serum lactic acid.The animals were then sacrificed and the small intestine was removed for determination of the malondialdehyde (MDA) content,and activities of superoxide dismutase (SOD),catalase (CAT) and glutathione peroxidase (GSH-Px) in intestinal tissues and for microscopic examination.The pathological changes of the intestinal epithelia were observed and the damage.to the mucous membrane was scored.The internal organs were removed and bacterial translocation from gut to the internal organs was observed.Results Compared with group S,the level of MDA and lactic acid,and rate of bacterial translocation were significantly increased,and the activities of SOD,CAT and GSH-Px were significantly decreased in groups I/R and HOS ( P ＜ 0.05).Compared with group I/R,the level of MDA and lactic acid,rate of bacterial translocation,and activities of SOD,CAT and GSH-Px were significantly decreased in group HOS ( P ＜ 0.05).Conclusion Intravenous infusion of HOS can reduce small intestinal I/R injury in rabbits.Key words: Oxygen; Infusions,intravenous; Reperfusion injury; Intestine, small" @default.
- W3029370014 created "2020-06-05" @default.
- W3029370014 creator A5009099160 @default.
- W3029370014 creator A5024773055 @default.
- W3029370014 creator A5039493947 @default.
- W3029370014 creator A5054499454 @default.
- W3029370014 creator A5066758438 @default.
- W3029370014 date "2012-07-20" @default.
- W3029370014 modified "2023-09-29" @default.
- W3029370014 title "Effect of intravenous infusion of hyper-oxygenated solution on small intestinal ischemia-reperfusion injury in rabbits" @default.
- W3029370014 doi "https://doi.org/10.3760/cma.j.issn.0254-1416.2012.07.028" @default.
- W3029370014 hasPublicationYear "2012" @default.
- W3029370014 type Work @default.
- W3029370014 sameAs 3029370014 @default.
- W3029370014 citedByCount "0" @default.
- W3029370014 crossrefType "journal-article" @default.
- W3029370014 hasAuthorship W3029370014A5009099160 @default.
- W3029370014 hasAuthorship W3029370014A5024773055 @default.
- W3029370014 hasAuthorship W3029370014A5039493947 @default.
- W3029370014 hasAuthorship W3029370014A5054499454 @default.
- W3029370014 hasAuthorship W3029370014A5066758438 @default.
- W3029370014 hasConcept C126322002 @default.
- W3029370014 hasConcept C134018914 @default.
- W3029370014 hasConcept C185592680 @default.
- W3029370014 hasConcept C2775838275 @default.
- W3029370014 hasConcept C2775920511 @default.
- W3029370014 hasConcept C2776151105 @default.
- W3029370014 hasConcept C2777397205 @default.
- W3029370014 hasConcept C2777882243 @default.
- W3029370014 hasConcept C2778401633 @default.
- W3029370014 hasConcept C2778760513 @default.
- W3029370014 hasConcept C2778979269 @default.
- W3029370014 hasConcept C2780114680 @default.
- W3029370014 hasConcept C2781046184 @default.
- W3029370014 hasConcept C2910216633 @default.
- W3029370014 hasConcept C2910951933 @default.
- W3029370014 hasConcept C3019368612 @default.
- W3029370014 hasConcept C42219234 @default.
- W3029370014 hasConcept C523546767 @default.
- W3029370014 hasConcept C541997718 @default.
- W3029370014 hasConcept C54355233 @default.
- W3029370014 hasConcept C71924100 @default.
- W3029370014 hasConcept C86803240 @default.
- W3029370014 hasConceptScore W3029370014C126322002 @default.
- W3029370014 hasConceptScore W3029370014C134018914 @default.
- W3029370014 hasConceptScore W3029370014C185592680 @default.
- W3029370014 hasConceptScore W3029370014C2775838275 @default.
- W3029370014 hasConceptScore W3029370014C2775920511 @default.
- W3029370014 hasConceptScore W3029370014C2776151105 @default.
- W3029370014 hasConceptScore W3029370014C2777397205 @default.
- W3029370014 hasConceptScore W3029370014C2777882243 @default.
- W3029370014 hasConceptScore W3029370014C2778401633 @default.
- W3029370014 hasConceptScore W3029370014C2778760513 @default.
- W3029370014 hasConceptScore W3029370014C2778979269 @default.
- W3029370014 hasConceptScore W3029370014C2780114680 @default.
- W3029370014 hasConceptScore W3029370014C2781046184 @default.
- W3029370014 hasConceptScore W3029370014C2910216633 @default.
- W3029370014 hasConceptScore W3029370014C2910951933 @default.
- W3029370014 hasConceptScore W3029370014C3019368612 @default.
- W3029370014 hasConceptScore W3029370014C42219234 @default.
- W3029370014 hasConceptScore W3029370014C523546767 @default.
- W3029370014 hasConceptScore W3029370014C541997718 @default.
- W3029370014 hasConceptScore W3029370014C54355233 @default.
- W3029370014 hasConceptScore W3029370014C71924100 @default.
- W3029370014 hasConceptScore W3029370014C86803240 @default.
- W3029370014 hasIssue "07" @default.
- W3029370014 hasLocation W30293700141 @default.
- W3029370014 hasOpenAccess W3029370014 @default.
- W3029370014 hasPrimaryLocation W30293700141 @default.
- W3029370014 hasRelatedWork W2058398071 @default.
- W3029370014 hasRelatedWork W2067793688 @default.
- W3029370014 hasRelatedWork W2338786610 @default.
- W3029370014 hasRelatedWork W2351547347 @default.
- W3029370014 hasRelatedWork W2354373418 @default.
- W3029370014 hasRelatedWork W2358124521 @default.
- W3029370014 hasRelatedWork W2363063493 @default.
- W3029370014 hasRelatedWork W2373517359 @default.
- W3029370014 hasRelatedWork W2375011942 @default.
- W3029370014 hasRelatedWork W2375159624 @default.
- W3029370014 hasRelatedWork W2379559852 @default.
- W3029370014 hasRelatedWork W2386874609 @default.
- W3029370014 hasRelatedWork W2390927852 @default.
- W3029370014 hasRelatedWork W2419314409 @default.
- W3029370014 hasRelatedWork W2614611029 @default.
- W3029370014 hasRelatedWork W3030255275 @default.
- W3029370014 hasRelatedWork W3030727166 @default.
- W3029370014 hasRelatedWork W3032133289 @default.
- W3029370014 hasRelatedWork W3032476208 @default.
- W3029370014 hasRelatedWork W3146079665 @default.
- W3029370014 hasVolume "32" @default.
- W3029370014 isParatext "false" @default.
- W3029370014 isRetracted "false" @default.
- W3029370014 magId "3029370014" @default.
- W3029370014 workType "article" @default.