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- W3029370415 abstract "目的:分析广西地区肝细胞癌中c-myc、N-ras癌基因的表达与乙型肝炎病毒(HBV)感染的关系及其在肝癌发生中的作用.方法:应用原位cDNA-RNA杂交方法和免疫组化方法检测40例广西地区肝癌和相应的癌旁组织中的c-myc mRNA、N-ras mRNA和HBsAg、HBxAg.结果:肝癌及癌旁组织均有较高的c-myc、N-ras癌基因的表达,其在不同分化程度肝癌中的表达差异无显著性意义:HBsAg和HBxAg的检出率分别为87.09%和79.31%.癌基因的表达与HB5Ag和HBxAg的检出率呈平行状态.结论:c-myc、N-ras在广西地区肝癌的形成和保持恶性表型中有协同作用.HBxAg可能有激活c-myc、N-ras癌基因的作用." @default.
- W3029370415 created "2020-06-05" @default.
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- W3029370415 date "2001-07-28" @default.
- W3029370415 modified "2023-09-25" @default.
- W3029370415 title "STUDY ON THE EXPRESSION OF IN SITU C-myc,N-ras ONCOGENES AND HEPATITIS B VIRUS INFECTION IN HEPATOCELLULAR CARCINOMA IN GUANGXI" @default.
- W3029370415 doi "https://doi.org/10.3760/cma.j.issn.1006-9801.2001.04.008" @default.
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