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- W3029382094 abstract "目的 探讨以中剂量环磷酰胺为主联合化疗加单一剂量重组人粒细胞集落刺激因子(G-CSF)对恶性血液病患者自体外周血造血干细胞的动员效果.方法 31例患者接受中剂量环磷酰胺2.2 g/m2 (1.8～3.0 g/m2)联合鬼臼乙叉甙(Vp16)600～800 mg(CE方案)或阿糖胞苷(Ara-C)1.0～2.0 g/m2 (CA方案) 化疗.预处理后,予以回输所采自体外周血造血干细胞,观察造血重建情况.结果动员所需时间(化疗开始至采集的平均时间)为(13.5±2.0)d,采集次数为 (2.9±1.0)次,WBC最低值为(0.95±1.0)×109/L,G-CSF开始给药时间为第(8.6±2.0)天,持续应用平均(7.4±2.0)d,采集到的单个核细胞数为(5.53±2.54)×108/L,CD34+细胞数为(9.46±7.24)×106/L,粒-单核细胞集落数为(46.02±70.58)×104/L.全部移植患者造血功能均获满意重建.结论中剂量环磷酰胺为主联合化疗(CE/CA)加单一剂量G-CSF对恶性血液病患者的造血干细胞动员是安全和有效的。" @default.
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- W3029382094 title "Effect of combined chemotherapy of middle-dose cyclophosphamide plus recombinant human granulocyte colony stimulating factor on autologous peripheral blood stem cells in patients with hematologic malignancies" @default.
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