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- W3029403375 abstract "ObjectiveTo explore the correlation of colorectal cancer and gallstone.MethodsThe gallstone incidence of 213 cases of colorectal cancer (C group) were compared with the same period of 432 cases of gastric cancer(G group). Patients with or without gallstone were also analyzed on the difference of gender, age, location of tumor, difference of the distribution and so on.Results(1)There were 41 cases with gallstone in C group(19.2%) and 37 cases in G group(8.6%). The ratio in C group was higher than that of G, χ2=15.318, P=0.000. (2) In C group, cases with gallstone had no significant difference in the anatomic site(χ2=5.386, P=0.068). While, the gallsone ratio was higher in female cases than that of male cases(χ2=11.056, P=0.001). The gallstone ratio was significantly different among 60 years sub-groups(χ2=10.557, P=0.005), and the ratio was higher in >60 years sub-groups. (3) Multivariate regression analysis suggested that overweight or hypertension, type 2 diabetes, abnormal liver function, alcohol, non-steroidal anti-inflammatory drugs and other conventional factors were not independent risk factors for colorectal cancer. While, dyslipidemia was an independent risk factor for colorectal cancer development(OR=2.742, 95% CI: 1.114-6.751, P=0.046).ConclusionGallstone is one of the risk factors for colorectal cancer, female, >60 years patients with gallstone has significantly increased risk of colorectal cancer. Gallbladder stones patients associated with dyslipidemia (high lipids) are susceptible to colorectal cancer.Key words: Colon cancer; Rectal cancer; Gallstone" @default.
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- W3029403375 date "2014-06-01" @default.
- W3029403375 modified "2023-09-24" @default.
- W3029403375 title "Preliminary study on the relation between colorectal cancer and gallstones in the HeXi Region of GanSu" @default.
- W3029403375 doi "https://doi.org/10.3877/cma.j.issn.1674-0793.2014.03.009" @default.
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