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- W3029414730 abstract "From bacteria to mammalian cells, protein-DNA interactions are indispensable for all living organisms. In order to perform cell growth, differentiation, division, and regulation of cell function when stimulated by the external environment, DNA-encoded genetic information must be accurately transcribed, which is extremely important for the growth, development, and evolution of organisms. Manipulating the interaction of protein and DNA through biotechnology can modulate the expression of certain virulence genes, so as to contributing to the treatment of diseases. With the deepening of scientific research, more and more scientific technologies are applied in the field of protein and DNA interaction research. In this paper, the principles, advantages, disadvantages and applications of commonly used techniques in the study of protein-DNA interactions were reviewed, which will help researchers evaluate and select appropriate methods in their researches.Key words: Protein; DNA; Interaction; Detection technology" @default.
- W3029414730 created "2020-06-05" @default.
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- W3029414730 date "2019-04-28" @default.
- W3029414730 modified "2023-09-27" @default.
- W3029414730 title "Research progress in the detection of DNA and protein interaction" @default.
- W3029414730 doi "https://doi.org/10.3760/cma.j.issn.1673-4181.2019.02.013" @default.
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