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- W3029450159 abstract "Objective To investigate the serum level of interleukin-10(IL-10)and interleukin-18(IL-18)and its clinical significance in patients with systemic lupus erythematosus(SLE).Methods The serum level of IL-10and IL-18 of 71 SLE patients(the active group 51 patients and stable group 20 patients)and 30 normal controls were measured by ELISA.Results The serum IL-10 and IL-18 level of the active SLE patients[(49.4±12.2)、(423.7+40.8)ng/L]were significantly higher than that of the stable SLE patients[(20.3±8.7);(241.6 ±29.1)ng/L]and control[(13.2±4.8);(150.3±21.6)ng/L](all P＜0.01).Conclusion IL-10 and IL-18 may play an important role in the pathogenesis of SLE and may be of useful clinical value in judsing SLE disease activity and its treatment.Key words: Lupus erythematosus,systemic; Interleukin-10; Interleukin18" @default.
- W3029450159 created "2020-06-05" @default.
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- W3029450159 date "2009-02-28" @default.
- W3029450159 modified "2023-09-23" @default.
- W3029450159 title "Serum Level of interleukin-10 and interleukin-18 in patients with systemic lupus erythematosus and its clinical significance" @default.
- W3029450159 doi "https://doi.org/10.3760/cma.j.issn.1008-6706.2009.02.028" @default.
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