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- W3029475768 abstract "Objective To evaluate the etficacy of dexmedetomidine combined with suffentanil on patient-controlled intravenous analgesia (PCIA) after operation.Methods Sixty ASA Ⅱ patients with gastric cancer aged 40 -60 years,weighting 45 -70 kg under went operation were randomly divided into two groups:group I (n =30),group Ⅱ ( n =30).Patients in group I received PCIA with suffentanil [background infusion 0.02 μg/(kg · h) ; bolus dose 0.025 μg/kg; locked interval 10 min].PCIA was performed with sufentanil 100 μg + ondansetron 8 mg in 100 ml of normal saline.A bolus of dexemedetomidine 1 μg/kg was given iv in group Ⅱ when the operation was going to be finished after a half.Dexmedetomidine at a rate of 0.2 μg/( kg · h) was also started to be infused intravenously at the beginning of PCIA in group Ⅱ.Ramsay score was recorded.The number of attempts,consumption of sufentanil and side effects such as vomiting and respiratory depression were recorded with 24 hours after operation.The level of sedation was evaluated according to Ramsay sedation score at 24 hours after operation.Results Compared with group I,the number of attempts,consumption of sufentanil were significantly decreased,Ramsay score and the satisfaction degrce were significantly increased in group Ⅱ.Conclusions The effect of dexmedetomidine combined with sufentanil for postoperative PCIA is better than the use single of sufentanil.Key words: Dexmedetomidine; Sufentanil ; Analgesia; Patient-controlled; Pain" @default.
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- W3029475768 date "2012-05-25" @default.
- W3029475768 modified "2023-09-24" @default.
- W3029475768 title "Efficacy of dexmedetomidine combined with suffentanil on patient-controlled intravenous analgesia after operations" @default.
- W3029475768 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2012.10.014" @default.
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