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- W3029485291 abstract "ObjectiveTo analyze the effect of imatinib combined with VP low dose regimen on adult Ph chromosome positive acute lymphoblastic leukemia.MethodsFrom June 2010 to June 2013, a total of 34 patients who accepted treatments were taken as the clinical research objects, and these patients were randomly divided into observation group (17 cases) and control group (17 cases). Patients in the control group were given VP low dose regimen, and the other patients in the observation group were given imatinib combined with VP low dose regimen. After treatment, the complete hematological remission rate, recurrence rate and adverse reaction rate was compared.ResultsThe complete hematological remission rate of the observation group was 88.24%, which was significantly higher than that of the control group (52.94%, P<0.05) ; the recurrence rate of the observation group was 17.65%, which was significantly lower than that of the control group (52.94%, P<0.05); the adverse reaction rate of the observation group was 11.76%, which was significantly lower than that of the control group (52.94%, P<0.05).ConclusionsImatinib combined with VP low dose regimen in the treatment of adult Ph chromosome positive acute lymphoblastic leukemia, has higher complete hematological remission rate, lower recurrence rate and adverse reaction rate, and can improve the survial rate of patients. So it is worthy of clinical application and promotion.Key words: Imatinib; VP low dose regimen; Ph chromosome positive acute lymphoblastic leukemia" @default.
- W3029485291 created "2020-06-05" @default.
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- W3029485291 date "2016-12-10" @default.
- W3029485291 modified "2023-09-28" @default.
- W3029485291 title "Effect of imatinib combined with VP low dose regimen on adult Ph chromosome positive acute lymphoblastic leukemia" @default.
- W3029485291 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2016.23.009" @default.
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