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- W3029515662 abstract "ObjectiveTwo kits for detecting anti-HAV antibody produced by Abbott Laboratories are evaluated for their performance in order to use in the anti-HAV antibodies detections.MethodsSerially diluted standard reference serum were detected 4 times with HAVAb2.0 kit and HAV-IgG kit , then fit standard curves and calculated Interclass correlation coefficient (ICC). 120 serum that have different levels of anti-HAV antibodies were chosen to be detected by two kits and calculated sensitivity and specificity, receive operation characteristic (ROC) curve and area under curve (AUC) while the results of HAV-IgG were used as golden standard.ResultsR2 and ICC for HAV-IgG were 0.9977 and 0.999, respectively, higher than 0.9893 and 0.995(P>0.05) for HAVAb2.0. Sensitivity and specificity for HAVAb2.0 were 93.15% and 100% and AUC was 0.994 when kit HAV-IgG was chosen as golden standard.ConclusionThere is little difference in performance between HAV-IgG and HAVAb2.0, both of them can be used in anti-HAV antibodies detection.Key words: Antibodies to hepatitis A virus; Diagnostic test; Reliability; Validity" @default.
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- W3029515662 date "2017-04-30" @default.
- W3029515662 modified "2023-09-27" @default.
- W3029515662 title "Comparisons for kits HAVAb2.0 and HAV-IgG" @default.
- W3029515662 doi "https://doi.org/10.3760/cma.j.issn.1003-9279.2017.02.019" @default.
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