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- W3029584530 abstract "百草枯(paraquat,PQ)是目前使用广泛的除草剂,对人畜具有较强毒性,可以引起肝、肾、肺等主要脏器损害,其中,肺组织纤维化损害最为严重,并呈现进行性发展过程[1],是导致重度患者死亡的首要原因.百草枯对人体损害极大,文献报道急性中毒病死率高达75％ ～ 80％[2],但目前仍缺乏特效解毒剂以及有效治疗手段.临床研究发现应用血必净注射液对PQ中毒肺纤维化患者进行干预治疗,取得了良好的效果,可以明显减轻患者肺纤维化程度及发生率[3],但其具体作用机制有待进一步阐明.笔者之前研究发现TNF-α和IL-10水平变化与百草枯中毒对肺脏损伤程度关系密切[4]。" @default.
- W3029584530 created "2020-06-05" @default.
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- W3029584530 date "2013-11-10" @default.
- W3029584530 modified "2023-09-25" @default.
- W3029584530 title "血必净注射液对急性百草枯中毒大鼠肺、血浆TNF-α和IL-10的影响" @default.
- W3029584530 doi "https://doi.org/10.3760/cma.j.issn.1671-0282.2013.11.006" @default.
- W3029584530 hasPublicationYear "2013" @default.
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