Matches in SemOpenAlex for { <https://semopenalex.org/work/W3029608977> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W3029608977 endingPage "618" @default.
- W3029608977 startingPage "594" @default.
- W3029608977 abstract "C-AMOX, a newly developed oral antibacterial agent, was evaluated experimentally and clinically for 178 patients with various infection, and results were as follows.Absorption and excretionMean serum concentration of C-AMOX reached to the peak level of 7.3 μg/ml, 3.3, μg/ml at four and six hours respectively after an oral administration of 500 mg to 6 healthy male volunteers. They decreased to 1.2, μg/ml and 0.24, μg/ml at ten hours after respectively.Mean urinary recovery rates were 69.1% and 63.4% respectively. In continuous administration of 500 mg and 1000 mg for 5 days at fasting, C-AMOX showed dose response and no cumulative tendency.Clinical evaluation1) C-AMOX was given orally to 500 mg (b.i.d.) to 178 cases, 109 cases with respiratory tract infection, 59 cases with urinary tract infection and 10 cases with enteritis. The clinical effects were excellent in 26 cases, good in 108 cases fair in 24 cases, and poor in 20 cases. Total clinical effectiveness rate of 75.3% was obtained.2) Bacteriological examination was carried out in 80 cases. The eliminative rate in gram positives was 85.7%, in gram negative 64.8% and in mixed isolates 58.3% respectively.3) Side effects were observed in each of one case of urticaria, nausea and soft stool, and three cases of stomach discomfort. Medication was continued except one case of nausea. In the laboratory findings, decrease of WBC count, increase of eosimocyte count, elevation of GOT value, elevation of GOT, GPT values, elevation of GPT, AL-P values, and increase of BUN, creatinine values in serum were observed in one case respectively." @default.
- W3029608977 created "2020-06-05" @default.
- W3029608977 creator A5001660970 @default.
- W3029608977 creator A5006580827 @default.
- W3029608977 creator A5008123577 @default.
- W3029608977 creator A5023249369 @default.
- W3029608977 creator A5025454788 @default.
- W3029608977 creator A5042262953 @default.
- W3029608977 creator A5048294923 @default.
- W3029608977 creator A5051207544 @default.
- W3029608977 creator A5052775128 @default.
- W3029608977 creator A5053017573 @default.
- W3029608977 creator A5056898222 @default.
- W3029608977 creator A5057850455 @default.
- W3029608977 creator A5064814889 @default.
- W3029608977 creator A5072381399 @default.
- W3029608977 creator A5073311324 @default.
- W3029608977 creator A5085972304 @default.
- W3029608977 creator A5087268632 @default.
- W3029608977 creator A5088569526 @default.
- W3029608977 creator A5088812262 @default.
- W3029608977 creator A5091362609 @default.
- W3029608977 date "1982-01-01" @default.
- W3029608977 modified "2023-10-14" @default.
- W3029608977 title "Fundmental and Clinical Studies on Continuous Preparation of Amoxicillin (C-AMOX) in the Fields of Internal Medicine" @default.
- W3029608977 doi "https://doi.org/10.11150/kansenshogakuzasshi1970.56.594" @default.
- W3029608977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6818297" @default.
- W3029608977 hasPublicationYear "1982" @default.
- W3029608977 type Work @default.
- W3029608977 sameAs 3029608977 @default.
- W3029608977 citedByCount "0" @default.
- W3029608977 crossrefType "journal-article" @default.
- W3029608977 hasAuthorship W3029608977A5001660970 @default.
- W3029608977 hasAuthorship W3029608977A5006580827 @default.
- W3029608977 hasAuthorship W3029608977A5008123577 @default.
- W3029608977 hasAuthorship W3029608977A5023249369 @default.
- W3029608977 hasAuthorship W3029608977A5025454788 @default.
- W3029608977 hasAuthorship W3029608977A5042262953 @default.
- W3029608977 hasAuthorship W3029608977A5048294923 @default.
- W3029608977 hasAuthorship W3029608977A5051207544 @default.
- W3029608977 hasAuthorship W3029608977A5052775128 @default.
- W3029608977 hasAuthorship W3029608977A5053017573 @default.
- W3029608977 hasAuthorship W3029608977A5056898222 @default.
- W3029608977 hasAuthorship W3029608977A5057850455 @default.
- W3029608977 hasAuthorship W3029608977A5064814889 @default.
- W3029608977 hasAuthorship W3029608977A5072381399 @default.
- W3029608977 hasAuthorship W3029608977A5073311324 @default.
- W3029608977 hasAuthorship W3029608977A5085972304 @default.
- W3029608977 hasAuthorship W3029608977A5087268632 @default.
- W3029608977 hasAuthorship W3029608977A5088569526 @default.
- W3029608977 hasAuthorship W3029608977A5088812262 @default.
- W3029608977 hasAuthorship W3029608977A5091362609 @default.
- W3029608977 hasBestOaLocation W30296089771 @default.
- W3029608977 hasConcept C126322002 @default.
- W3029608977 hasConcept C2777056448 @default.
- W3029608977 hasConcept C2779708577 @default.
- W3029608977 hasConcept C2780026642 @default.
- W3029608977 hasConcept C2780580376 @default.
- W3029608977 hasConcept C501593827 @default.
- W3029608977 hasConcept C71924100 @default.
- W3029608977 hasConcept C77411442 @default.
- W3029608977 hasConcept C86803240 @default.
- W3029608977 hasConcept C89423630 @default.
- W3029608977 hasConcept C90924648 @default.
- W3029608977 hasConceptScore W3029608977C126322002 @default.
- W3029608977 hasConceptScore W3029608977C2777056448 @default.
- W3029608977 hasConceptScore W3029608977C2779708577 @default.
- W3029608977 hasConceptScore W3029608977C2780026642 @default.
- W3029608977 hasConceptScore W3029608977C2780580376 @default.
- W3029608977 hasConceptScore W3029608977C501593827 @default.
- W3029608977 hasConceptScore W3029608977C71924100 @default.
- W3029608977 hasConceptScore W3029608977C77411442 @default.
- W3029608977 hasConceptScore W3029608977C86803240 @default.
- W3029608977 hasConceptScore W3029608977C89423630 @default.
- W3029608977 hasConceptScore W3029608977C90924648 @default.
- W3029608977 hasIssue "7" @default.
- W3029608977 hasLocation W30296089771 @default.
- W3029608977 hasLocation W30296089772 @default.
- W3029608977 hasOpenAccess W3029608977 @default.
- W3029608977 hasPrimaryLocation W30296089771 @default.
- W3029608977 hasRelatedWork W11389301 @default.
- W3029608977 hasRelatedWork W2043304778 @default.
- W3029608977 hasRelatedWork W2083653180 @default.
- W3029608977 hasRelatedWork W2169049798 @default.
- W3029608977 hasRelatedWork W2270196194 @default.
- W3029608977 hasRelatedWork W2380085882 @default.
- W3029608977 hasRelatedWork W3213079831 @default.
- W3029608977 hasRelatedWork W4288392727 @default.
- W3029608977 hasRelatedWork W797757511 @default.
- W3029608977 hasRelatedWork W1946186729 @default.
- W3029608977 hasVolume "56" @default.
- W3029608977 isParatext "false" @default.
- W3029608977 isRetracted "false" @default.
- W3029608977 magId "3029608977" @default.
- W3029608977 workType "article" @default.