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- W3029624923 abstract "ObjectiveTo describe the detection and clinical characterization of emerging respiratory virus in PICU.MethodsNasopharyngeal aspirates specimens (NPA) were collected from 600 children who were admitted to PICU with acute respiratory tract infection in our hospital. Additional 87 NPA were collected from healthy children for routine examination in the physical examination center. The clinical datas were collected. Multiplex PCR was applied to detect emerging respiratory virus. Some sequences were identified by using DNA sequencing. And the clinical data of positive cases were analysed.Results(1) There were 114 positive samples (19%) in 600 NPA, including 48 (8.00%) human bocavirus (HBoV), 47 (7.83%) human rhinovirus group C (HRV-C), 13 (2.17%) swine H1N1 (SWH1N1), 10 (1.67%) human metapneumovirs (HMPV), 3 (0.50%) WU polyomaviruses (WUPyV). But none from 87 healthy controls were positive for any respiratory virus. (2) Co-infection by at least 2 viral pathogens under study was observed in 45 of the 114 positive cases, including 22 (45.83%, 22/48) HBoV, 14 (29.78%, 14/47) HRV-C, 4 (4/13) SWH1N1, 9 (9/10) HMPV, 3 (3/3) WU polyomaviruses.ConclusionThe emerging viruses, such as HBoV, HMPV, HRV-C, SWH1N1, have high detection rate in PICU, may lead to severe infection. The clinical doctors should pay attention to them.Key words: Emerging virus; Respiratory virus; Pediatric intensive care unit" @default.
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- W3029624923 date "2014-03-20" @default.
- W3029624923 modified "2023-09-29" @default.
- W3029624923 title "Detection and clinical characterization of emerging respiratory virus in PICU" @default.
- W3029624923 doi "https://doi.org/10.3760/cma.j.issn.1673-4912.2014.03.001" @default.
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