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- W3029627402 abstract "ObjectiveTo understand the molecular epidemiology of norovirus from 5 outbreaks of gastroenteritis during Dec. 2012 to Jan. 2013 in Guangzhou.MethodsEpidemiologic data and specimens were collected from 5 gastroenteritis outbreaks in Guangzhou. 274 specimens were detected for norovirus by RT-PCR methods and PCR products were sequenced. Sequence alignment and phylogenetic analysis were performed by using Clustal X 1.83 and MEGA 5.05 programs. Statistical analysis was performed by using SPSS 17.0 program.ResultsThe total positive rate of norovirus was 20.07% (55/274). The positive rate was 8.70% (2/23) in University A, 36.36% (8/22) in Kindergarten B, 36.07% (22/61) in University C, 100% (5/5) in community health service center D, 11.04% (18/163) in University E. The positive rate was 100% (6/6) among age group ≥ 60 years old, 47.37% (9/19) among 10-19 age group and 36.36% (8/22) among age group<10 years old. Phylogenetic analysis showed that 33 samples were infected by the new variant-Sydney 2012 of norovirus GII.4.ConclusionNorovirus was one of the main pathogens causing acute gastroenteritis outbreaks and GII.4 Sydney 2012 variant was identified as the predominant strain in Guangzhou.Key words: Norovirus; Acute gastroenteritis; Outbreak; Sydney 2012 variant" @default.
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- W3029627402 date "2016-04-30" @default.
- W3029627402 modified "2023-09-24" @default.
- W3029627402 title "Molecular epidemiology of Norovirus from acute gastroenteritis outbreaks in Guangzhou" @default.
- W3029627402 doi "https://doi.org/10.3760/cma.j.issn.1003-9279.2016.02.014" @default.
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