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- W3029632160 abstract "There are many single nucleotide polymorphism (SNP) markers available, due to the improved high-throughput genotyping technology. Currently, in the genome research, haplotype analysis has been applied to the association analysis between the SNP loci and complex traits. Existing haplotyping methods include population-based methods, pooled DNA methods, and methods for family and pedigree data. Family and pedigree datasets are abundant and have unique advantages. Currently there are many haplotyping methods for family and pedigree data that have been developed. We review the haplotyping methods and the corresponding computer programs suitable for family and pedigree data, discuss their applications and limitation, and describe the challenges that remain to be addressed.Key words: Pedigree ; Haplotype inference ; Linkage disequilibrium" @default.
- W3029632160 created "2020-06-05" @default.
- W3029632160 creator A5075503256 @default.
- W3029632160 date "2011-08-15" @default.
- W3029632160 modified "2023-09-28" @default.
- W3029632160 title "Research progress on methods for haplotyping in pedigrees" @default.
- W3029632160 doi "https://doi.org/10.3760/cma.j.issn.1673-4386.2011.04.003" @default.
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