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- W3029673956 abstract "ObjectiveTo explore the recurring risk factors for sacrococcygeal teratoma (SCT) in children.MethodsA retrospective review was conducted for 107 SCT children between January 2003 and December 2012 at our hospital. Risk factors were identified by univariate and multivariate analyses.ResultsSixteen children had a recurrence of SCT at a median interval of 16.25 (6-59) months after primary surgery. And the Altman types of recurrent tumors were Ⅰ(n=8, 15.4%), Ⅱ(n=2, 10.5%), Ⅲ(n=1, 10.0%) and Ⅳ(n=5, 31.3%). Histologically, there were mature teratoma (n=8), immature teratoma (n=2) and malignant teratoma (n=5). Over half of recurrences showed a shift towards histological immaturity or malignancy as compared with primary tumor. The recurring risk factors were spillage of tumor parenchyma (P=0.028), incomplete resection (P=0.000) and immaturity (P=0.029) and malignant histology (P=0.026). Size, Altman classification and age were not recurring risk factors.ConclusionsTumor recurrence is an important prognostic factor for children with sacrococcygeal teratoma. The recurring risk factors include tumor spillage, malignancy or incomplete resection. Regular postoperative follow-ups are conducive for early detection of tumor recurrence and improving curative rate.Key words: Sacrococcygeal teratoma; Relapse; Risk factors" @default.
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- W3029673956 date "2016-09-15" @default.
- W3029673956 modified "2023-09-24" @default.
- W3029673956 title "Recurring risk factors for sacrococcygeal teratoma in children" @default.
- W3029673956 doi "https://doi.org/10.3760/cma.j.issn.0253-3006.2016.09.006" @default.
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