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- W3029737107 abstract "A 61-year-old male patient with type 2 diabetes received an oral metformin 850 mg about 30 minutes after drinking about 400 ml liquor containing 52% of alcohol into an empty stomach. About 4 hours later, the patient developed stuffy pain below xiphoid process and palpitation, and about 7 hous later, he developed nausea and vomiting. The laboratory examination showed that the blood pH 7.16, lactic acid 15.0 mmol/L, base excess -12.6 mmol/L, bicarbonate 15 mmol/L. He was diagnosed as diabetic lactic acidosis. Comprehensive treatments such as oxygen inhalation, acidosis correction, fluid infusion were given and metformin was changed to oral rosiglitazone 4 mg once daily. Eighteen hours later, the discomfort below xiphoid process was markedly improved, nausea and vomiting did not recur, his laboratory examination results showed the blood pH 7.41, lactic acid 1.8 mmol/L, base excess 2.3 mmol/L, and bicarbonate 27 mmol/L.Key words: Metformin; Acidosis, lactic; Alcohol drinking" @default.
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- W3029737107 date "2017-08-28" @default.
- W3029737107 modified "2023-09-28" @default.
- W3029737107 title "Lactic acidosis induced by metformin and a large amount of alcohol drinking into an empty stomach" @default.
- W3029737107 doi "https://doi.org/10.3760/cma.j.issn.1008-5734.2017.04.015" @default.
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