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- W3029759390 abstract "Objective To study the correlation between MMP-9 rs3918242 C ＞ T polymorphism and cancer risk.Methods PubMed database was utilized to search the relative artiles concerning association between MMP-9 rs3918242 C ＞T polymorphism and cancer risk (last search updated on April 2011).All the statistical analysis was performed by STATA software.Results 4,124 cancer patients and 4,728 control subjects were included in this meta-analysis.No association was observed in the overall analysis (allelic contrast P=0.378,OR =0.94,95％ CI:0.83-1.07).However,in the stratified analysis by cancer type,MMP-9-1562 T allele was found to decrease the lung cancer(P =0.026,OR =0.70,95％ CI:0.5 1-0.96) and colorectal cancer(P=0.016,OR =0.80,95％ CI:0.66-0.96).Conclusion MMP-9 rs3918242 C/T polymorphism is correlated with colorectal cancer and lung cancer.Key words: Matrix metalloproteinase 9; Polymorphism,single nucleotide; Neoplasms; Meta-analysis" @default.
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- W3029759390 date "2012-12-08" @default.
- W3029759390 modified "2023-09-24" @default.
- W3029759390 title "MMP-9 gene polymorphism and cancer risk: a meta-analysis" @default.
- W3029759390 doi "https://doi.org/10.3760/cma.j.issn.1673-422x.2012.012.020" @default.
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